ID   A0A1I5FDK2_9BRAD        Unreviewed;       923 AA.
AC   A0A1I5FDK2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SFO21834.1};
GN   ORFNames=SAMN05216330_102257 {ECO:0000313|EMBL:SFO21834.1};
OS   Bradyrhizobium sp. Ghvi.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=1855319 {ECO:0000313|EMBL:SFO21834.1, ECO:0000313|Proteomes:UP000198509};
RN   [1] {ECO:0000313|EMBL:SFO21834.1, ECO:0000313|Proteomes:UP000198509}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ghvi {ECO:0000313|EMBL:SFO21834.1,
RC   ECO:0000313|Proteomes:UP000198509};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FOVU01000002; SFO21834.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I5FDK2; -.
DR   STRING; 1855319.SAMN05216330_102257; -.
DR   Proteomes; UP000198509; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd12914; PDC1_DGC_like; 1.
DR   CDD; cd12915; PDC2_DGC_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 3.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF12860; PAS_7; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          360..400
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          514..647
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          656..906
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   923 AA;  101825 MW;  0BB3DE382A7EB4C8 CRC64;
     MLQGSLDDPD VCTATIDMMT GYGSRLLDHA FVRSGPIRWL VVGGILLIAA IAVGAVLMAQ
     NFRERALRNS GRELENTVLL LAHHFDQQLQ DFAVIQRDFV DHVRAIGVAD ADDYRKRLAG
     QDIHRMLRSK IEALPYIGGV NVIDDQGNVI NSSMAWPSPK VNVADRAYFR TFKYDPQAPD
     VLIEPLYSRI SGQWTILIVR KIVGPNGEFI GAVGRGIEPA GFEKFFASVV LGEGGTISML
     HRDGTLLARY PHSSELMGRN FKSGSFEQQR VFGLDHFAGR FISPVDGEDR LISARALPHF
     PILMMATMTR AAALTDWREQ IGILISTAGA SALAIASVLI AIVRKLLEQH RMSRERLTLE
     KQRLDRAVNN MTQGLLLVDA SQQLVVCNQR YIEMYGLAPE VVKPGCSFRE VIAHRKQTGS
     FTGDVDQYVA LVLRDIHVRN SMVVDTADGR SIQIVNEPLA DGGWVATHED ITERRRIEER
     ITHLAHYDAL TDLPNRTMFH EHLRGELAAI ADGEELAVHY IDIDEFKGVN DALGHLVGDE
     LLKSVAESLR SCAGPTDFVA RLGGDEFAIV QSAVSSQDQV IELVARVFAS IRAPFDCMGH
     HLTTDASIGI ALAPGHGTAL DQLLKNADMA MYAAKSAGRR TYRFFEPEMD AKVRERRQLE
     IDLRHAIACG ELEVFYQPCL SLKDDRITGC EALVRWRHPE RGMVSPAEFI PIAEDTGLIN
     EIGEWVLATA CRDAAGWPDD IRLAVNVSPV QFKSGTLALK IMAALAASNL PASRLELEIT
     EAVLIRDDDT ALAILHELRA IGVRIALDDF GTGYSSLSYL HRFPFDKIKI DRCFVEDIAG
     PDGSASIVQA VVNLASARRM ATTAEGVETE EQQRLLRALG CTEMQGYLFS AAKTADKVVE
     LFALHRSRLA QRGGSEARRR EAG
//