ID A0A1I5HM57_9ACTN Unreviewed; 450 AA.
AC A0A1I5HM57;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Thioredoxin reductase {ECO:0000313|EMBL:SFO49398.1};
GN ORFNames=SAMN04489713_106322 {ECO:0000313|EMBL:SFO49398.1};
OS Actinomadura madurae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=1993 {ECO:0000313|EMBL:SFO49398.1, ECO:0000313|Proteomes:UP000183413};
RN [1] {ECO:0000313|EMBL:SFO49398.1, ECO:0000313|Proteomes:UP000183413}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43067 {ECO:0000313|EMBL:SFO49398.1,
RC ECO:0000313|Proteomes:UP000183413};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOVH01000006; SFO49398.1; -; Genomic_DNA.
DR RefSeq; WP_075021798.1; NZ_FOVH01000006.1.
DR AlphaFoldDB; A0A1I5HM57; -.
DR STRING; 1993.SAMN04489713_106322; -.
DR eggNOG; COG0446; Bacteria.
DR InParanoid; A0A1I5HM57; -.
DR Proteomes; UP000183413; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR017224; Opine_Oxase_asu/HCN_bsu.
DR PANTHER; PTHR42949; ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT B; 1.
DR PANTHER; PTHR42949:SF2; ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT B; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PIRSF; PIRSF037495; Opine_OX_OoxA/HcnB; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000183413}.
FT DOMAIN 4..315
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 368..417
FT /note="BFD-like [2Fe-2S]-binding"
FT /evidence="ECO:0000259|Pfam:PF04324"
FT REGION 421..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 46815 MW; 4DB04AA5CF055D1E CRC64;
MTWHVVVVGA GPAGLCAAAG ALRAGSEVTL VDAAPEPGGQ NRAWHGYERL RDHVLGRPRC
DWWPQSAVWS IDRAGDGPPH VHVLRGEIDG AERDRHVLRP GALVLAPGAH DRVLPFPGWE
LPGVSTAGAA QSFVKREGLP PGDRTLIAGS GPFLLPVAAS LLEAGASVRA VLEANPAATV
ARGWTRRPWE LAAQTGKAAE LAGYAALLAR HRVPYRTGRA VIEARGDGRI EEAVTARLRA
DWSAVPGTEQ VVAVDALCVA HGFTPRLELP VAAGCRLRGG AFVEVDADQR TSVPGVHAAG
EITGIAGAPA ARAEGLLAGW TAGLGSPDAP AAVAARRRRD RARAFAARLA AAHPIGAAWP
GWLRPDTIVC RCEDTPYGAL PCALGTGSAH AVKLATRAGL GPCQARICGP TVAELLRSGH
PHHRPIAQPV RLGELARPPV EDPGTKESSP
//
