ID A0A1I5I5D7_9ACTN Unreviewed; 495 AA.
AC A0A1I5I5D7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase {ECO:0000313|EMBL:SFO55773.1};
GN ORFNames=SAMN04489713_107138 {ECO:0000313|EMBL:SFO55773.1};
OS Actinomadura madurae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=1993 {ECO:0000313|EMBL:SFO55773.1, ECO:0000313|Proteomes:UP000183413};
RN [1] {ECO:0000313|EMBL:SFO55773.1, ECO:0000313|Proteomes:UP000183413}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43067 {ECO:0000313|EMBL:SFO55773.1,
RC ECO:0000313|Proteomes:UP000183413};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; FOVH01000007; SFO55773.1; -; Genomic_DNA.
DR RefSeq; WP_075021941.1; NZ_FOVH01000007.1.
DR AlphaFoldDB; A0A1I5I5D7; -.
DR STRING; 1993.SAMN04489713_107138; -.
DR InParanoid; A0A1I5I5D7; -.
DR Proteomes; UP000183413; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11699:SF291; NADP_NAD-DEPENDENT ALDEHYDE DEHYDROGENASE PUUC; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000183413}.
FT DOMAIN 20..487
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 259
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 495 AA; 52498 MW; 547815174FB08474 CRC64;
MDALEFVKSV PTQAFIDGAF VDPASRGTLD SFAPATGEIF AQIADCGEAD VDAAVAAARK
AFDDGRWSRL APEKRKAAML GFADLIESRS QQFIDIESID AGKPVHDLET IDVPHVVSTI
RHYAEMIDKV YGKVAPTSEK NLALVVKEPV GVVGAVLPWN FPIAIASQKL GPALAAGNSV
VVKPPEQASL STIYLAQLAA EAGIPDGVIN VLPGRGEIAG RALGLHMDVD AITFTGSTAV
GQAFLRYSSE SNMKRVVLEC GGKSAGIVLS DAGRNLEAVA LQTSIAGFWN AGQNCTCGSR
ILVHKSLHKD FVETLSAIAS QWKVGSPRDS ESQIGPIIEA SALDRILGHI DEAAASGAQV
AFGGKRLYEE TGGWFVQPTV IDNVRPGQRI WREEVFGPVV GVTPFETDDE AVALANDSSY
GLHATLYTHD LDRAVKVSRR VRAGVIAVNE YSEGSLATPF GGYKMSGFGG HDNGTEALEQ
YTETKTIWMA LGDDA
//
