ID A0A1I5JY63_9ACTN Unreviewed; 509 AA.
AC A0A1I5JY63;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN ORFNames=SAMN05660464_1127 {ECO:0000313|EMBL:SFO77754.1};
OS Geodermatophilus dictyosporus.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Geodermatophilus.
OX NCBI_TaxID=1523247 {ECO:0000313|EMBL:SFO77754.1, ECO:0000313|Proteomes:UP000198857};
RN [1] {ECO:0000313|Proteomes:UP000198857}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44208 {ECO:0000313|Proteomes:UP000198857};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOWQ01000001; SFO77754.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5JY63; -.
DR STRING; 1523247.SAMN05660464_1127; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000198857; Unassembled WGS sequence.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR044638; ALDH7A1-like.
DR PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000198857}.
FT DOMAIN 32..488
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 262
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 509 AA; 52969 MW; E828721A055B34D2 CRC64;
MTSLPTAEEL RALAREAAGR CGVDLDAVAG DHPVTSPLTG TPLASVRWDT GADVGTAVAR
AGEAFRTWRT TPAPVRGQLV RRLGELLREH KADLATLVSL EVGKITSEAA GEVQEMVDIC
EFAVGLSRQL YGRTISSERP GHRLMETWHP LGVVGVISAF NFPVAVWSWN TAVALVCGDP
VVWKPSELAP LSALAAAALL DRAIAETGAP AGLSQVVLGG GDVGEALVDS PGVALLSATG
STRMGRVVGP RVADRFGRSL LELGGNNAAI VTPSADLDLA TRGIVFSAAG TAGQRCTTMR
RVIAHVDVVD ALVERVAAAY RNLPIGSPIA AGTLVGPLVH DAAYKAMQDA LEAARQQGGE
VVAGGGRRLA DEAPDAYYAE PALVRMPAQT DVVRHETFAP ILYVLPYRTL EEAVALNNDV
PQGLSSSIFT SDQAEAERFL AADGSDCGIA NVNIGTSGAE IGGAFGGEKH TGGGRESGSD
AWKAYMRRAT NTINYSGQLP LAQGVEFPI
//
