ID A0A1I5MQL3_9BACT Unreviewed; 457 AA.
AC A0A1I5MQL3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Tryptophanase {ECO:0000313|EMBL:SFP11597.1};
GN ORFNames=SAMN04515674_101397 {ECO:0000313|EMBL:SFP11597.1};
OS Pseudarcicella hirudinis.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Pseudarcicella.
OX NCBI_TaxID=1079859 {ECO:0000313|EMBL:SFP11597.1, ECO:0000313|Proteomes:UP000199306};
RN [1] {ECO:0000313|EMBL:SFP11597.1, ECO:0000313|Proteomes:UP000199306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E92,LMG 26720,CCM 7988 {ECO:0000313|Proteomes:UP000199306};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR611166-50};
CC -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC {ECO:0000256|ARBA:ARBA00009721}.
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DR EMBL; FOXH01000001; SFP11597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5MQL3; -.
DR STRING; 1079859.SAMN04515674_101397; -.
DR OrthoDB; 9764079at2; -.
DR Proteomes; UP000199306; Unassembled WGS sequence.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR GO; GO:0009072; P:aromatic amino acid metabolic process; IEA:InterPro.
DR CDD; cd00617; Tnase_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR011166; Beta-eliminating_lyase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR018176; Tryptophanase_CS.
DR PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF001386; Trpase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00853; BETA_ELIM_LYASE; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR611166-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000199306}.
FT DOMAIN 46..422
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 257
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR611166-50"
SQ SEQUENCE 457 AA; 51115 MW; AF67FF1F77E5BB59 CRC64;
MTTIIEPFRI KSVEPIKFTN ETERKTILKD TGYNPFLIHA DDVMIDLLTD SGTSAMSSKQ
WAGIMDGDES YAGSRSFFRF EEAVKRITGM DFVIPTHQGR AAEKILFSIL GGKGKFFPNN
THFDTTRANI EYSGAEAVDL LCEVGKHPEE KADFKGNMDL DKLRAFILEK GPENIPLVFI
TITNNSGGGQ PVSMENIKGV RKICDEFGLK FFIDACRFAE NAYFIKIREK GYESKSVLEI
CRELFSYADG MTMSAKKDAL VNIGGFLALN DDKLAMNCRN VLIVTEGFPT YGGLAGRDLE
AIAQGLEEIT DENYLHYRIR SVEYLGEKLL AAGVPLIEPT GGHAVYLDAK RFCPHIPAEE
FPGQAVSIAL YEKGGIRACE IGSVMFGKYD EKGKLIPPPM ELVRLAIPRR VYTQSHIDYV
AEIIIAVFNE RHLLKGYKLS YEAPMLRHFT ARFELAD
//
