ID A0A1I5N9R9_9ACTN Unreviewed; 303 AA.
AC A0A1I5N9R9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Transcriptional regulator, IclR family {ECO:0000313|EMBL:SFP18588.1};
GN ORFNames=SAMN04489713_11272 {ECO:0000313|EMBL:SFP18588.1};
OS Actinomadura madurae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=1993 {ECO:0000313|EMBL:SFP18588.1, ECO:0000313|Proteomes:UP000183413};
RN [1] {ECO:0000313|EMBL:SFP18588.1, ECO:0000313|Proteomes:UP000183413}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43067 {ECO:0000313|EMBL:SFP18588.1,
RC ECO:0000313|Proteomes:UP000183413};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOVH01000012; SFP18588.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5N9R9; -.
DR STRING; 1993.SAMN04489713_11272; -.
DR eggNOG; COG1414; Bacteria.
DR InParanoid; A0A1I5N9R9; -.
DR OrthoDB; 8479143at2; -.
DR Proteomes; UP000183413; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000183413};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 36..98
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 99..281
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 303 AA; 31996 MW; 6615CFC6E1017DE0 CRC64;
MERTTGAPSP RAPSKPARPR GGTVDDDRPA AANYHANALA RGLALLERLA ERGGTLTLND
FNAGTGLPKS TLVRLLGVLE EMGYVVRADE RPAYRLGHKT LMLSTAYLTG LDLSQVAGGH
LAGVAEDTGQ TANLGVLDGR EVLHVCVREP DRPIRFHTTP GTRDAAYCTG LGKMLLAHLD
PSELGPHLPP EPFPARTEHT LTSTEALVRD LRETARRGHA VDDNEGSVGL RCVAAPVEVD
GVCVAAVSVS GPSAEFDDAR RAGYLDRLRA AAAGLAADAD VVAALDYLRS SLRPGAPRPR
EDA
//
