ID A0A1I5NVB0_9PSED Unreviewed; 295 AA.
AC A0A1I5NVB0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=DNA-3-methyladenine glycosylase II {ECO:0000256|ARBA:ARBA00012000};
DE EC=3.2.2.21 {ECO:0000256|ARBA:ARBA00012000};
GN ORFNames=SAMN05216190_10778 {ECO:0000313|EMBL:SFP25181.1};
OS Pseudomonas borbori.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=289003 {ECO:0000313|EMBL:SFP25181.1, ECO:0000313|Proteomes:UP000198784};
RN [1] {ECO:0000313|Proteomes:UP000198784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17834 {ECO:0000313|Proteomes:UP000198784};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-
CC methylguanine, 7-methylguanine and 7-methyladenine.; EC=3.2.2.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000086};
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DR EMBL; FOWX01000007; SFP25181.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5NVB0; -.
DR STRING; 289003.SAMN05216190_10778; -.
DR OrthoDB; 9811249at2; -.
DR Proteomes; UP000198784; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR CDD; cd00056; ENDO3c; 1.
DR Gene3D; 3.30.310.20; DNA-3-methyladenine glycosylase AlkA, N-terminal domain; 1.
DR Gene3D; 1.10.1670.10; Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal); 1.
DR InterPro; IPR010316; AlkA_N.
DR InterPro; IPR037046; AlkA_N_sf.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR003265; HhH-GPD_domain.
DR InterPro; IPR023170; HhH_base_excis_C.
DR PANTHER; PTHR43003; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR PANTHER; PTHR43003:SF13; DNA-3-METHYLADENINE GLYCOSYLASE 2; 1.
DR Pfam; PF06029; AlkA_N; 1.
DR SMART; SM01009; AlkA_N; 1.
DR SMART; SM00478; ENDO3c; 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
DR SUPFAM; SSF55945; TATA-box binding protein-like; 1.
PE 4: Predicted;
FT DOMAIN 8..125
FT /note="DNA-3-methyladenine glycosylase AlkA N-terminal"
FT /evidence="ECO:0000259|SMART:SM01009"
FT DOMAIN 135..293
FT /note="HhH-GPD"
FT /evidence="ECO:0000259|SMART:SM00478"
SQ SEQUENCE 295 AA; 32157 MW; 9FD1610E32D90D75 CRC64;
MNNAPQTTLL LPYHAPWEWQ QFHDHFALRA LAGVERLGRE HYCRSFRLGT VSGWFRVSPQ
PGQNALALSY SASAIPCLAE LQQRVRRMFD LDAEPQRIGR HFAQDPYLAT LIARNPGLRL
PTAFDPFEQA VRAIVGQQVT VKAAVSISGR LVARLGEPLP AADGAGVDRL FPSAAAIAGA
DLAGIGMPGK RVQTLQHFAG LIASGALHLD LRHGSEALIE RLCALPGIGP WTAEYIALRA
FGAADAFPAS DLGLLKAPLW GADGIDARQL KARAEAWRPW RAYAAAHLWH NYSQR
//
