ID A0A1I5P444_9BRAD Unreviewed; 1109 AA.
AC A0A1I5P444;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=SAM domain (Sterile alpha motif) {ECO:0000313|EMBL:SFP28610.1};
GN ORFNames=SAMN05216330_106272 {ECO:0000313|EMBL:SFP28610.1};
OS Bradyrhizobium sp. Ghvi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=1855319 {ECO:0000313|EMBL:SFP28610.1, ECO:0000313|Proteomes:UP000198509};
RN [1] {ECO:0000313|EMBL:SFP28610.1, ECO:0000313|Proteomes:UP000198509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ghvi {ECO:0000313|EMBL:SFP28610.1,
RC ECO:0000313|Proteomes:UP000198509};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOVU01000006; SFP28610.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5P444; -.
DR STRING; 1855319.SAMN05216330_106272; -.
DR OrthoDB; 9785312at2; -.
DR Proteomes; UP000198509; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd09487; SAM_superfamily; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 1..60
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 78..207
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 1109 AA; 121060 MW; E3AD959B5B25951B CRC64;
MQIAEWLGKL GLGQYAERFA QNGIDVDVLP ELMDEDFDKL GVLLGHRRKM LRAIADLDPA
ALIASPTPAH DAERRHLTIM FCDLVGSTAL TARLDPEDMW EVIRTYRAAC ARVIAAYDGK
IVRFVGDGIL VYFGYPRAHE DDAERAVRTG LDIISAIRQL KTGAGELVEL RIAIATGLVV
VGDLISGEAS EEHATVGDTP NLAARLQSIA EPGVVVVASS TRRLLGDLFT FRNLGRREVK
GIGEPIAVWA VEGATASESR FEAVRAARSI GFVGRKDEIE FILSRQREAW QGRGQIVLIS
GEAGIGKSRI VATLSESPSL GTHRRVRYQC SPYHTNSALH PFVAQLERAA GIRSLDTPEQ
KLDKLEAMLA LGTQQVAQAT SLIAALLSIP TGDHRAPLGL SPAQQRRQTF AVLLDQLEGL
ARDQPLLIIC EDLHWADATT LELLDLAVDR IRALPILVLM TSRPEFEPSW SGLSNVGLLR
LDRLDRQDTR ALVEQVVVGR QLPRELMKQI IDKTDGVPLF VEELTKMVLE SGLLVEDAGR
YRLNSPLPPL AIPATLQDSL MARLDRLAPV KEVAQIGAAI GRDFSYVLLK YVAGRDDLTL
SAALEQLEEA ELLLRRGSPP DANYSFKHAL VQEAAYGSLL KSKRQLLHTR IGEVLREKFP
VVAETEPEVL AHHFTEAGLC EVALEWWRKA GQLALKRSAY SEAVAHLGKA VATADELADG
SRLMMTRLHL QISYGRALRG RLGHSAPETI AAWTRARQFA ADIDDPVELA PVHSGLFNAC
LTQGELAPMQ ELADAIRGAA DRWPDSPVAA VVAHWTGGVT CWFAGDYVNA RTHLERALAI
YGAEPDPATF RASALDLPFV IMRFLALVLW PLGITARARR LAAEAVGAPG ETRALSRANA
LVHRAVFDGV CGGMLQQTET ILALGLARDH TMPLYVAAGT YLNGLAKWRA GDRTAGLADM
RHGWTLLHEN DCYLCEPFWG MHVAVANAEA GEVETGLEIL SDVIARTAQS GQHWLDAELH
RVRGRLLSRH GSSDESSAED DLKRALEIAR HQQTKTFELR SALGLAHLHK ANGRAGAASE
VLAPILAEFE AERDLPEVAE AKELLGDGR
//
