ID   A0A1I5P664_9ACTN        Unreviewed;       489 AA.
AC   A0A1I5P664;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Halogenation protein CepH {ECO:0000313|EMBL:SFP29588.1};
GN   ORFNames=SAMN04489713_11315 {ECO:0000313|EMBL:SFP29588.1};
OS   Actinomadura madurae.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=1993 {ECO:0000313|EMBL:SFP29588.1, ECO:0000313|Proteomes:UP000183413};
RN   [1] {ECO:0000313|EMBL:SFP29588.1, ECO:0000313|Proteomes:UP000183413}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43067 {ECO:0000313|EMBL:SFP29588.1,
RC   ECO:0000313|Proteomes:UP000183413};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the flavin-dependent halogenase family.
CC       Bacterial tryptophan halogenase subfamily.
CC       {ECO:0000256|ARBA:ARBA00038396}.
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DR   EMBL; FOVH01000013; SFP29588.1; -; Genomic_DNA.
DR   RefSeq; WP_075023190.1; NZ_UAPP01000012.1.
DR   AlphaFoldDB; A0A1I5P664; -.
DR   STRING; 1993.SAMN04489713_11315; -.
DR   GeneID; 73575333; -.
DR   eggNOG; COG0644; Bacteria.
DR   InParanoid; A0A1I5P664; -.
DR   Proteomes; UP000183413; Unassembled WGS sequence.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   Gene3D; 3.30.9.100; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006905; Flavin_halogenase.
DR   PANTHER; PTHR43747:SF1; FAD-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR   Pfam; PF04820; Trp_halogenase; 2.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183413}.
SQ   SEQUENCE   489 AA;  53119 MW;  C6C2A6AC5191A28A CRC64;
     MSSSTAESFD IVVIGGGPGG STVSTLTAKQ GHRVLLLERD TFPRYQIGES LLPATAHGIA
     RLLGVDEELR SAGFTRKKGG TFRWGSNPEP WTFSFAVSPK LAGPTSFAYQ VERMKFDQIL
     LDNARRHGVE VREESTVIGV LEDEGRIGGV RYVDADGNEH TVESAFVVDA SGNTGRTYRH
     VGGERRYSEF FRNLALFGYF EGGKRLPAPN SGNILSAAFE DGWFWYIPLS PTLTSVGAVV
     HRDAASKVQG DREAALNRLI EACPLIKEYL AGARRVTSGP YGELRVRKDY SYCNTRFWRP
     GMVLVGDAAC FVDPVFSSGV HLATYSGLLA ARSVNSCLAG TVGEKEAFQE FERRYRREYG
     VFYEFLVSFY GMQADERSYF WAAKKVTNYP DSELEAFVEL VGGLASGDVI DATPQSVSEE
     LVSGTEALAA AGRSGTDSGD LHGRPVVANA MAESANMQAE VLLGVEPAPL FPDGLVSTPD
     GLHWTHPSA
//