ID   A0A1I5PKZ4_9BURK        Unreviewed;       867 AA.
AC   A0A1I5PKZ4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Sulfite reductase (NADPH) flavoprotein alpha-component {ECO:0000313|EMBL:SFP34196.1};
GN   ORFNames=SAMN05443579_110262 {ECO:0000313|EMBL:SFP34196.1};
OS   Variovorax sp. PDC80.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=1882827 {ECO:0000313|EMBL:SFP34196.1, ECO:0000313|Proteomes:UP000199369};
RN   [1] {ECO:0000313|Proteomes:UP000199369}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PDC80 {ECO:0000313|Proteomes:UP000199369};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOWG01000010; SFP34196.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I5PKZ4; -.
DR   Proteomes; UP000199369; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd06200; SiR_like1; 1.
DR   Gene3D; 3.40.50.360; -; 1.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR001094; Flavdoxin-like.
DR   InterPro; IPR008254; Flavodoxin/NO_synth.
DR   InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR005625; PepSY-ass_TM.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   PANTHER; PTHR34219:SF3; BLL7967 PROTEIN; 1.
DR   PANTHER; PTHR34219; IRON-REGULATED INNER MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF00258; Flavodoxin_1; 1.
DR   Pfam; PF03929; PepSY_TM; 1.
DR   PRINTS; PR00369; FLAVODOXIN.
DR   PRINTS; PR00371; FPNCR.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR   SUPFAM; SSF52218; Flavoproteins; 1.
DR   SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
DR   PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE   4: Predicted;
KW   Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199369};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022982}.
FT   TRANSMEM        12..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        145..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          402..540
FT                   /note="Flavodoxin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50902"
FT   DOMAIN          560..728
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51384"
SQ   SEQUENCE   867 AA;  93821 MW;  2B105C54AFE7B9DF CRC64;
     MTMPTWRQAW FQLHWLLGIT AGSVLLVIGL SGAVLSFREE LIDALNPGGR HVAVQDKEAL
     APPQLLAAVR EAFPGRQVGT LALFAEPGAA ARVIFAPRPG ERRGDTVYLD PYAGRPLPPL
     AGAEFFEWVE ALHRWLLLPR EPGRVAAGVL AIGLFVLALS GLYLRWPRRP LDWRAWLTFD
     PALKGRPFLW GLHSVAGTCA LLLYLVFTTT GVYWAFDAVR DRVDAFAGQP RAPAQARNAP
     RVRNMQRDDA GAVDVAPAWA TFQRQAAASG WSEVILRVPT GAAPTVLFTW LDAHPAHERA
     RNRMTVRLPG GEVAQDERHD AKPMGGRFLA AIYPLHMGTY FGLPGRIAMM LAALMLPVFT
     VTGWMLYLDR RRKKRAVAAE RAALAAGAGR PSADGATAPE GVLVAFASQS GTAEGIALRS
     AAALEAGGLR VTVASLARLD PEQLRHHQRL LLVASSFGEG GPPDAARRFA QRLVQVGGDA
     LAHLRYGLLA LGDRHYARFC GFGHALDHAL VAAGAQSLFP MIEVDNGDTA ALARWRRQLV
     TLRGADAVPA EALADEPLAP AFEPWTLSAR RLLNPGSLGA PLYEIELAAP PEAAAAWRPG
     ALAELQPRLA ADTVAALLRA TSWTADAPVV FQGRHCTLAE ALARSAVPAP QALVQGLDAQ
     ALADALVPLA TRRYSIASLP SEGHVRLLVR QARHEQGLGI ASGWLTAHAP LMAPVPLRLL
     PNPGFAPVAD DRPCIFVGNG SGYAGLRGHL RERIERGHRR NWLVFGERQL ARDAFFMDEL
     RHWQAAGQVE RVDLAFSRDH APRIYVQDRL REHAGDLRRW VGEGAAIFVC GSLHGMAAGV
     DEALEAALGR ATLDDLIAEG RYRRDVY
//