ID A0A1I5RYR6_9RHOB Unreviewed; 892 AA.
AC A0A1I5RYR6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN04488047_109139 {ECO:0000313|EMBL:SFP63136.1};
OS Tranquillimonas alkanivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Tranquillimonas.
OX NCBI_TaxID=441119 {ECO:0000313|EMBL:SFP63136.1, ECO:0000313|Proteomes:UP000199356};
RN [1] {ECO:0000313|EMBL:SFP63136.1, ECO:0000313|Proteomes:UP000199356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19547 {ECO:0000313|EMBL:SFP63136.1,
RC ECO:0000313|Proteomes:UP000199356};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FOXA01000009; SFP63136.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5RYR6; -.
DR STRING; 441119.SAMN04488047_109139; -.
DR OrthoDB; 9796100at2; -.
DR Proteomes; UP000199356; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000199356};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 203..254
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 251..328
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 329..383
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 456..508
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 521..744
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 764..880
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 814
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 892 AA; 96049 MW; 732ECD17BB505F8A CRC64;
MKVTHGIVAP RVWLPVSAAL WLAAALLETL TPLGVTHGSL YLFPLMAVAA SGQRTPVIVV
AALSAVATAA GFLVHEHGVS RSLELLDRAI TITLLGAFSV MALTLQEALA RARRGEAAAQ
RSIEALARAE ATLQHAEGTG PIGSLHLDLA SGELRWSDGL FRIFGLESGG CLSMADVTAR
LHPGDRAGFD NALSDALDRG ERLEHEHRIV RAGDGAVRRV ALIAEKVEGE GGAYLAGVVQ
DVTDQRVRER RLRLLSSAVA MLDEIVLITE ADSLDSPEGP RIVYVNDAFE RITGYTREQA
LGQTPRMLQG PCTQRAELDR LRAALEKAEP VSVELINYRA DGEEYWLEIS VSPVRDERGR
LTHFVAVQRD VTRRKKNLEA LREVEERYRL VTQATSDVVW DWDMQTGGMW YSDSVLAMLG
TRIDSLDAWL ARVHPDDRAH VEATNARMLE GADTVVEDEY RLRRADGTYI RVKDRAFVQR
DAAGRPLRML GTMQDVTEAR EMEARLSRAE TLQAVGTLTG GVAHDINNLM TVVLGNADLL
DEELEAQPGA RAKVDQIAGA AERAAALTGR LLAFAREQPL EPRSVDVPAL VEQLLPILRT
SLPDSVSLRV QALPGLPPAH VDPGQLEVAL LNLVVNARDA MPRGGVIDIG ITFDRPDGRS
DPLDGRPLPD ECLIVSVKDH GTGMTPEVLS KALDPFFTTK PPGAGTGLGL SMAYGFAKQS
GGHIELSSTP RQGTTVRIFL PAASVPAIAR AARPDAPAAG GGEHVLLVED DRDVRAATER
QLAALGYRVS SAEDAAEAMA ALEAHPDVAL LLTDLVLSGG MNGRELAERA REENPDLRVL
YASGYAEAQV LAHDRPDPQV PLLRKPFRRA ALAAAVGGAL AGQSSSTETV RK
//
