ID   A0A1I5S7F8_9FIRM        Unreviewed;       674 AA.
AC   A0A1I5S7F8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer with Cache sensor {ECO:0000313|EMBL:SFP66738.1};
GN   ORFNames=SAMN05444406_10224 {ECO:0000313|EMBL:SFP66738.1};
OS   Caldicoprobacter faecalis.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Caldicoprobacteraceae;
OC   Caldicoprobacter.
OX   NCBI_TaxID=937334 {ECO:0000313|EMBL:SFP66738.1, ECO:0000313|Proteomes:UP000198577};
RN   [1] {ECO:0000313|EMBL:SFP66738.1, ECO:0000313|Proteomes:UP000198577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20678 {ECO:0000313|EMBL:SFP66738.1,
RC   ECO:0000313|Proteomes:UP000198577};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; FOXR01000002; SFP66738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I5S7F8; -.
DR   STRING; 937334.SAMN05444406_10224; -.
DR   OrthoDB; 13222at2; -.
DR   Proteomes; UP000198577; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198577};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        270..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        293..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          314..366
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          385..642
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   674 AA;  74115 MW;  6BF21BB545342D1E CRC64;
     MIIPISILGY YSRDKAEKAI QQTAAQSTIQ TMEQMSQYLS LVFSTVEEIS MQIFSNKDIQ
     DFLLIREDQL TTYDYHQMRQ KVQSVLSNYT MNNKFIDNII LLIDEKRSIA TGNISLSNLN
     FEDIKNAEWY KAAIEGNGKI IWRGSHPELD TSATSKTAYC MSGIRAIKHL SSGTIFGVLL
     IDVKYEPIMD ILKKANLGSR SEIHLIGPDG HALSSETGEQ INEDESVTTH NITEHDFYQE
     IISSEEPAGY KEVTHHGQKW LMIYNRVGET GYTLVGLILN SVLFAATQEI ARTTIMLMVF
     ACIFALIVGL YMSNSMGRTI ARIINAAEKV AMGDLTVNPV SRRRDELGVL TRSINSMIAN
     MRQLIQQTAA LAHKVVESSS TVASTSQQLS ASSQEIAKAI QEIAQGAAEQ AADAEQGVQK
     MDMLAAKINS VSDNARDIHN LSKETMNLTQ QGLDAVDQLE QKARQTTAIT QEILADIDTL
     NQHSQAIGKI IKVIDNIADQ TNLLALNAAI EAARAGEMGK GFAVVANEIR KLAEQSMSAT
     REITAIIKNT QQQTAQTVKR AKSAEDIVKS QNEAVVTTIS AFKQIAASAE TLVNRVEQII
     QGVNEMENDK NQAVLAMQNI SAVSQEAAAS SQEVTASTEE QLSGVEQLAS YAEELNYAAQ
     ELMQAISKFK IEQN
//