ID A0A1I5T4F5_9FIRM Unreviewed; 265 AA.
AC A0A1I5T4F5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=5-proFAR isomerase {ECO:0000256|ARBA:ARBA00031376};
GN ORFNames=SAMN04487928_1086 {ECO:0000313|EMBL:SFP77893.1};
OS Butyrivibrio proteoclasticus.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio.
OX NCBI_TaxID=43305 {ECO:0000313|EMBL:SFP77893.1, ECO:0000313|Proteomes:UP000182624};
RN [1] {ECO:0000313|Proteomes:UP000182624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P18 {ECO:0000313|Proteomes:UP000182624};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- SIMILARITY: Belongs to the HisA/HisF family.
CC {ECO:0000256|ARBA:ARBA00009667, ECO:0000256|RuleBase:RU003657}.
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DR EMBL; FOXO01000008; SFP77893.1; -; Genomic_DNA.
DR RefSeq; WP_074886102.1; NZ_FOXO01000008.1.
DR AlphaFoldDB; A0A1I5T4F5; -.
DR OrthoDB; 9807749at2; -.
DR Proteomes; UP000182624; Unassembled WGS sequence.
DR GO; GO:0003949; F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity; IEA:InterPro.
DR GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd04723; HisA_HisF; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR011858; His6-like_euk.
DR InterPro; IPR006062; His_biosynth.
DR InterPro; IPR044524; Isoase_HisA-like.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR NCBIfam; TIGR02129; hisA_euk; 1.
DR PANTHER; PTHR43090; 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE; 1.
DR PANTHER; PTHR43090:SF2; 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE; 1.
DR Pfam; PF00977; His_biosynth; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605,
KW ECO:0000256|RuleBase:RU003657};
KW Histidine biosynthesis {ECO:0000256|ARBA:ARBA00023102,
KW ECO:0000256|RuleBase:RU003657}; Isomerase {ECO:0000313|EMBL:SFP77893.1}.
SQ SEQUENCE 265 AA; 28848 MW; F89A03E26214D723 CRC64;
MKLRPCIDIH NGKVKQIVGS SLVDDGDMAR ENYVSSKDAA FYSNMYRELG LSGGHVILLN
AVDSPYYEMT KQQAIGALMA NPGLLQVGGG ITADNAQEFI EAGASHVIVT SYVFKNGKIS
YTNLKKLLKA VGKERIVLDL SCKAKNDKDV HVQGASYYIV TDRWQKMSDV RLCNETLEEL
SNYCDEFLVH AADVEGKQNG IEEKVVKVLA DWGKIPITYA GGVGKISDIE KLKKLGKGKL
DVTIGSALDI FGGHLVMNDV IAACD
//
