ID A0A1I5UAR7_9FIRM Unreviewed; 509 AA.
AC A0A1I5UAR7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Cardiolipin synthase {ECO:0000313|EMBL:SFP92360.1};
GN ORFNames=SAMN02910358_00101 {ECO:0000313|EMBL:SFP92360.1};
OS Lachnospiraceae bacterium XBB1006.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1520827 {ECO:0000313|EMBL:SFP92360.1, ECO:0000313|Proteomes:UP000199554};
RN [1] {ECO:0000313|EMBL:SFP92360.1, ECO:0000313|Proteomes:UP000199554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XBB1006 {ECO:0000313|EMBL:SFP92360.1,
RC ECO:0000313|Proteomes:UP000199554};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOXT01000004; SFP92360.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5UAR7; -.
DR STRING; 1520827.SAMN02910358_00101; -.
DR OrthoDB; 9762009at2; -.
DR Proteomes; UP000199554; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR CDD; cd09154; PLDc_SMU_988_like_1; 1.
DR CDD; cd09160; PLDc_SMU_988_like_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR022924; Cardiolipin_synthase.
DR InterPro; IPR027379; CLS_N.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR Pfam; PF13396; PLDc_N; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000199554};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 244..271
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 422..449
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 509 AA; 58251 MW; C96FA60E160ADA74 CRC64;
MNKLRKLLSS RLVIWGVMML VQIGWFISIF SYFNTHFRYA GTCLEAIAVV IVLTIVNKQT
NPSYKVAWSI LILGVPVLGI AMYFLFGRSD ITKRNRRKLD KMHSKSIRHL NHNDHVFEEL
AKCSRGASKQ SGYISRWSHF PVYENQGLTY YSTGDDTLEP ILEAIAKAEH YIFLEFFIIG
EGVFFNSILD ALEEKAKQGV EVRLMYDDFG SANTVPHHYD RDIEQRGISC VRFNTLKPLF
SAVMNNRDHR KIIIIDGKVA FTGGFNLADE YINKRHRFGH WKDNGLRIEG EAVANFVAMF
LEMWQYSTGD SEDEAGYFPS YESKQSLPGF VQPFADSPLD HEKVGETVYL NIINRAKDYL
YIFTPYLIID NEMMTALCNA AKSGVDVRIV TPGIPDKKLV FLLTQSYYGQ LLQAGVRIFQ
YSPGFIHAKT FVCDDVIATV GTINLDYRSL YMHFECGVWM YGTWEVGQIK QDALETFDVS
KEITYAHELA RSPIIKSLQG ILRLFAPIM
//
