ID   A0A1I5URJ1_9PSEU        Unreviewed;       482 AA.
AC   A0A1I5URJ1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=MFS transporter, SHS family, sialic acid transporter {ECO:0000313|EMBL:SFP97812.1};
GN   ORFNames=SAMN05421810_10487 {ECO:0000313|EMBL:SFP97812.1};
OS   Amycolatopsis arida.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=587909 {ECO:0000313|EMBL:SFP97812.1, ECO:0000313|Proteomes:UP000198727};
RN   [1] {ECO:0000313|Proteomes:UP000198727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.5579 {ECO:0000313|Proteomes:UP000198727};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FOWW01000004; SFP97812.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I5URJ1; -.
DR   STRING; 587909.SAMN05421810_10487; -.
DR   OrthoDB; 9787026at2; -.
DR   Proteomes; UP000198727; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd17316; MFS_SV2_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR005828; MFS_sugar_transport-like.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR23508; CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG; 1.
DR   PANTHER; PTHR23508:SF3; SIALIC ACID TRANSPORTER NANT; 1.
DR   Pfam; PF00083; Sugar_tr; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198727};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        22..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        88..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        113..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        146..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        224..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        247..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        311..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        341..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        406..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        431..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..458
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
SQ   SEQUENCE   482 AA;  51150 MW;  E291C2DD10321A95 CRC64;
     MATEPPGVPQ SFRQLSGGQR KAFFAAWLGY LLDGFDFILI TLVLTEIADD FDLDLTTAAT
     LVSAAFVSRW LGGLVLGAIG DRFGRKPAMI LAILAFSVGS GLCGFAWGYW SLFVFRAIVG
     IGMAGEYGSS ATYVMESWPK AMRNRATGFL LSAYPIGTVL AALSYEVIVP DLGWRWLFYV
     GIVPIALALY LRRSLPEAAE WTAEVAGRRD VTTSSVLFTP RRRLGNGLLA AVLATALVLV
     FSENSGGVSW LLVAVVVAGF VAFAVQLAGR LWPVMLAIMV TVFCAFLYSW PIQSLLPTYL
     KTELGYDAGQ VSNALTWAGL GYAAGSCLAG VLGDRLGTRR AYVLGLFVSL AFVFPVFALP
     AGNIVLLWVL LFAMQATSQG ISGLLPKYIA DHFPTRLRAA GLGFSYNVGA LGGAVAPLAG
     AAIAADLGDL GTALTTLAVT LTVTVALIIG FDLPARIGRW LRVSTDISAD TPARTSTDRT
     TP
//