ID A0A1I5VPV2_9PSED Unreviewed; 232 AA.
AC A0A1I5VPV2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:SFQ09482.1};
GN ORFNames=SAMN05216190_13246 {ECO:0000313|EMBL:SFQ09482.1};
OS Pseudomonas borbori.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=289003 {ECO:0000313|EMBL:SFQ09482.1, ECO:0000313|Proteomes:UP000198784};
RN [1] {ECO:0000313|Proteomes:UP000198784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17834 {ECO:0000313|Proteomes:UP000198784};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOWX01000032; SFQ09482.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5VPV2; -.
DR STRING; 289003.SAMN05216190_13246; -.
DR OrthoDB; 9803687at2; -.
DR Proteomes; UP000198784; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:SFQ09482.1};
KW Transferase {ECO:0000313|EMBL:SFQ09482.1}.
FT DOMAIN 11..105
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 105..232
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 232 AA; 25102 MW; 79AFE19F50A4346A CRC64;
MTEQFNEEDF DLNDLPDDEL VEQVHDDLYN GLREEVVEST EILLARGWSA SKVLDEALVG
GMGIVGVDFR DGILFVPEVL MAANAMKGGM EVLRPLLSQA GAESVGKIVI GTVKGDIHDI
GKNLVCMMME GAGFEVIDIG INIPVEEYIA ALEKHKPDIL GLSALLTTTM SYMKVVIDTL
VEKGIRDDYI VMVGGAPLNE EFGKAVGADV YCRDAGVAVD MAKELIARRR AA
//
