ID A0A1I5VYD8_9BRAD Unreviewed; 347 AA.
AC A0A1I5VYD8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SFQ12471.1};
GN ORFNames=SAMN05216330_11640 {ECO:0000313|EMBL:SFQ12471.1};
OS Bradyrhizobium sp. Ghvi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=1855319 {ECO:0000313|EMBL:SFQ12471.1, ECO:0000313|Proteomes:UP000198509};
RN [1] {ECO:0000313|EMBL:SFQ12471.1, ECO:0000313|Proteomes:UP000198509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ghvi {ECO:0000313|EMBL:SFQ12471.1,
RC ECO:0000313|Proteomes:UP000198509};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FOVU01000016; SFQ12471.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5VYD8; -.
DR STRING; 1855319.SAMN05216330_11640; -.
DR OrthoDB; 9793626at2; -.
DR Proteomes; UP000198509; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR CDD; cd05299; CtBP_dh; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR043322; CtBP.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719}.
FT DOMAIN 31..113
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 114..292
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 347 AA; 38134 MW; ED866B850976B10E CRC64;
MPKYKVVTPK GASFTVAGSD YSYEREALDP IDAEIVEAPA NEAEFIAAAK HADAIYAKGI
PITKTIIDAL ENCKVITLGS VGVDSVDVKA ATARGIPVTN IPDTFIEEVA DHAMMLLLSG
FRRLVEQDRM VRTGRWAEGR PALLKIPRLM GQTLGFISFG RVARAVAKRA APFGLRMMAY
DPFIQETLMW DHGVIPATLN EVLSQSDFVS MHAPARPEVH HMLTEKHFRQ MKKGSIFINT
GRGATVDEEG LIKALQEGWI AHAALDVLEK EPPSHNNPIL SMENVTLTAH VASASARFDE
ARKRRVGYEL SLVLQGMWPV SCVNPSVLQD TALRRWQPVG MDRGPNS
//
