ID A0A1I5WJA4_9LACT Unreviewed; 729 AA.
AC A0A1I5WJA4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=HD/PDEase domain-containing protein {ECO:0000259|SMART:SM00471};
GN ORFNames=SAMN04488506_0912 {ECO:0000313|EMBL:SFQ19730.1};
OS Desemzia incerta.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae; Desemzia.
OX NCBI_TaxID=82801 {ECO:0000313|EMBL:SFQ19730.1, ECO:0000313|Proteomes:UP000199136};
RN [1] {ECO:0000313|EMBL:SFQ19730.1, ECO:0000313|Proteomes:UP000199136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20581 {ECO:0000313|EMBL:SFQ19730.1,
RC ECO:0000313|Proteomes:UP000199136};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOXW01000003; SFQ19730.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5WJA4; -.
DR STRING; 82801.SAMN04488506_0912; -.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000199136; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199136};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 512..668
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
SQ SEQUENCE 729 AA; 81723 MW; 99E8E6F20C0DC604 CRC64;
MMKVFTIVKN KLGKFFIPLI MLLFSSVLFA LMYSGLKPDV LDIQLYEVAD TTIRANSTVE
DTAQTEINQK IAAENVAPVY SFNSELKNKQ LSKVQLLFVT IEEIQKLEKA RTTKPEGNDG
ENDPAAVVEE EPLTTEEKYS LFQEKTNNLE QAAQDFIAEI PEWIIVELLN TPSDTLTKLS
DLVTTITSEK MSEPIRADQL KETIEDAQDT IQYSDLDNSY QRIGYLIVDQ AIVENNIYND
QATEQARQQA MDNVQPVMIL QGQVIVQEGH VVDSTDIHHL ELLGMLDNEP SYQMLYSLLV
LLAAQITGIY YITKIETTSS EKMTKIIVLY SLLVIVSVAI MKGLQLLQLA GINNIAFLYP
AALAPMLANA FLSSRFSYFL NSFLPVFSIF VFADYKGTTS ALIIAVVYSL NGLFGAFTKQ
RKEQIISGSL LWLMIIGNGI VMLSMILYLN QPVFTAQTLM MLVYSILGGI LSYVFSIMLI
PYIDVYYDDK AVLTMNELSN PNQPLLKLLL TKAPGTYHHS LMVANLSSNA VSAIGGDSLF
TRVACYYHDV GKLTHPLFFV ENLPSGMDNP HRLLSPYESK DIILGHVSEG VRILKEANMP
ESIIDICAQH HGTTLVKYFY AEAKKENPDV DESEFRYPGP KPQSREAAII NIADSAEAAC
RSMSNPTKKS IEDFVHSLIA ERFREGQFNE CSITMEELHI VENSLVESLV GTFHSRIEYP
KMEPHNEKS
//
