ID A0A1I5WZA4_9ACTN Unreviewed; 126 AA.
AC A0A1I5WZA4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Arsenical resistance operon repressor {ECO:0000256|ARBA:ARBA00039566};
GN ORFNames=SAMN04489713_12540 {ECO:0000313|EMBL:SFQ25000.1};
OS Actinomadura madurae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=1993 {ECO:0000313|EMBL:SFQ25000.1, ECO:0000313|Proteomes:UP000183413};
RN [1] {ECO:0000313|EMBL:SFQ25000.1, ECO:0000313|Proteomes:UP000183413}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43067 {ECO:0000313|EMBL:SFQ25000.1,
RC ECO:0000313|Proteomes:UP000183413};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOVH01000025; SFQ25000.1; -; Genomic_DNA.
DR RefSeq; WP_075024556.1; NZ_UAPP01000009.1.
DR AlphaFoldDB; A0A1I5WZA4; -.
DR STRING; 1993.SAMN04489713_12540; -.
DR GeneID; 73574177; -.
DR eggNOG; COG0640; Bacteria.
DR InParanoid; A0A1I5WZA4; -.
DR OrthoDB; 9798835at2; -.
DR Proteomes; UP000183413; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR018334; ArsR_HTH.
DR InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; NF033788; HTH_metalloreg; 1.
DR PANTHER; PTHR33154:SF18; ARSENICAL RESISTANCE OPERON REPRESSOR; 1.
DR PANTHER; PTHR33154; TRANSCRIPTIONAL REGULATOR, ARSR FAMILY; 1.
DR Pfam; PF01022; HTH_5; 1.
DR PRINTS; PR00778; HTHARSR.
DR SMART; SM00418; HTH_ARSR; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00846; HTH_ARSR_1; 1.
DR PROSITE; PS50987; HTH_ARSR_2; 1.
PE 4: Predicted;
KW Arsenical resistance {ECO:0000256|ARBA:ARBA00022849};
KW Reference proteome {ECO:0000313|Proteomes:UP000183413};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 27..124
FT /note="HTH arsR-type"
FT /evidence="ECO:0000259|PROSITE:PS50987"
SQ SEQUENCE 126 AA; 13416 MW; F58035CCDD198809 CRC64;
MSKQPLPILG PVDAEGACCA PLVCEPLSEN EAAELAPLFK AIADPVRLRL LSLIACHEGG
EVCVCDLTAA FDLTAPTISH HLKVLKQAGL IDSERRGTWV YYWLNPGVLE RLSTILGPRV
AAAAVS
//
