ID   A0A1I6EC50_9FIRM        Unreviewed;       960 AA.
AC   A0A1I6EC50;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Phage terminase-like protein, large subunit, contains N-terminal HTH domain {ECO:0000313|EMBL:SFR15285.1};
GN   ORFNames=SAMN05660706_13511 {ECO:0000313|EMBL:SFR15285.1};
OS   Desulfoscipio geothermicus DSM 3669.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfallaceae;
OC   Desulfoscipio.
OX   NCBI_TaxID=1121426 {ECO:0000313|EMBL:SFR15285.1, ECO:0000313|Proteomes:UP000199584};
RN   [1] {ECO:0000313|Proteomes:UP000199584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 3669 {ECO:0000313|Proteomes:UP000199584};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOYM01000035; SFR15285.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6EC50; -.
DR   STRING; 39060.SAMN05660706_13511; -.
DR   OrthoDB; 9760250at2; -.
DR   Proteomes; UP000199584; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR   Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003587; Hint_dom_N.
DR   InterPro; IPR036844; Hint_dom_sf.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR006141; Intein_N.
DR   InterPro; IPR004860; LAGLIDADG_2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR046461; TerL_ATPase.
DR   InterPro; IPR046462; TerL_nuclease.
DR   InterPro; IPR005021; Terminase_largesu-like.
DR   PANTHER; PTHR41287; -; 1.
DR   PANTHER; PTHR41287:SF1; PROTEIN YMFN; 1.
DR   Pfam; PF14528; LAGLIDADG_3; 1.
DR   Pfam; PF03354; TerL_ATPase; 1.
DR   Pfam; PF20441; TerL_nuclease; 1.
DR   SMART; SM00306; HintN; 1.
DR   SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR   SUPFAM; SSF55608; Homing endonucleases; 2.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR   PROSITE; PS50817; INTEIN_N_TER; 1.
PE   4: Predicted;
KW   Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW   Protein splicing {ECO:0000256|ARBA:ARBA00023000};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199584}.
FT   DOMAIN          258..426
FT                   /note="DOD-type homing endonuclease"
FT                   /evidence="ECO:0000259|PROSITE:PS50819"
SQ   SEQUENCE   960 AA;  109457 MW;  3AFCF80FE8B4D83D CRC64;
     MSQPNYILEY WNKIQSGEIV ACKRLVQQYQ KLVDELNNPR DPWVFDLEKA NQPIEFIEKF
     CKHSKGKWIG KPVELGLFQK AKIQAVYGFV HKDTGVRRCR EVFTCVARKN GKALSVDTPI
     ITPDGWKVMG ELNVGDYIYG ADGKPARIKF TSEIFNDHTC YEVEFEDGEK IIADAEHVWT
     VITKNSRRML KRKLKGTRKL QRTDYREGNG YFNITTEEMA KDFARVRKDG KGIEYKYRVP
     INKAIEFPRA NLPIDPYVLG VWLGDGSSCS GRITINWQDS QILDEIKKAG YVLIKRETDK
     KAGTVTITND KSKYCIRGHL KSENFNYKTN KCLACEKMTG YARRHGLEIP PYTNLSLQGN
     LRALNLLNNK HIPKMYLMSS VDQRMELLRG LMDTDGYVEK RGQCEFVQKS KVIIDGFSEL
     LLSLGIKHSI REKTAKCNGK DAGTVYSVLF YCDKTNPCFK LQRKLDRLKD KLCSRMANKS
     IVNIKKVDTV PTKCIGVDNA DNLYLAGKRM TVTHNSTEKA ATGNYMLIGD GEGGAEVYSV
     ATKKDQARIV FTEAVNMISQ SPALSKHIKK RKTDLYFPVT FSKFEPLASD SNSLDGLNTH
     YCVMDELHAI KDRNLYDVMK QSMAAREQPL LDMITTAGFV RECIFDDIYD YACKVLDGVI
     EDERFLAFIY ELDDRNEWTD FRAWEKANPG LGTIKSYEEL AANVERAKHD KNFLPTVLTK
     DFNIRETTAD KWLTFEEANN EEVFDIEELR DCYGIGGVDL GATTDLTFAG ILIMKPGSEQ
     KYFVGQGFMP ADTIEQRSKE DKVPYDKWAE RGLITPCPGN KVDYRYVTDW FLKMRDEYGI
     IAYWSGYDSW NSPAWVEDME NRIGYTNKEN LIPVIMGART LSAPMKELKA DLAANGINYN
     NNPLVKWALT NVAVEVDKNE NIRPVKGKNQ RQRIDPAVAL LIAYTVLTNN LEDYKGLIGG
//