ID A0A1I6EXU0_9PSEU Unreviewed; 975 AA.
AC A0A1I6EXU0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=DNA-binding transcriptional activator of the SARP family {ECO:0000313|EMBL:SFR22481.1};
GN ORFNames=SAMN04488564_106188 {ECO:0000313|EMBL:SFR22481.1};
OS Lentzea waywayandensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=84724 {ECO:0000313|EMBL:SFR22481.1, ECO:0000313|Proteomes:UP000198583};
RN [1] {ECO:0000313|EMBL:SFR22481.1, ECO:0000313|Proteomes:UP000198583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44232 {ECO:0000313|EMBL:SFR22481.1,
RC ECO:0000313|Proteomes:UP000198583};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; FOYL01000006; SFR22481.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6EXU0; -.
DR STRING; 84724.SAMN04488564_106188; -.
DR Proteomes; UP000198583; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000313|EMBL:SFR22481.1};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 16..81
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|SMART:SM00862"
FT DOMAIN 88..215
FT /note="Bacterial transcriptional activator"
FT /evidence="ECO:0000259|SMART:SM01043"
FT REPEAT 743..776
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 975 AA; 106766 MW; 0ADAEFBB4659AA59 CRC64;
MRSFGLLGPL DVVLDGRHVH IPPGKRRVVL AALLLRPGQV VGVDELVELA GGSRNALQTT
VGRLREVLPG LVLTKPGGYL LDVLPDEVDV HRFDRLEPRE ALALWRGRPF ADIGSDALER
DHVPALTEKY LATLEARIET DLRDGEHERL VPELRSLTRQ NPTRERMWAQ LIVALHRCDR
QTEALQAYDD IRGRLAGELG LDPGKDLQKA HQQVLTADNR PRARNDLPGD IADFAGRASD
LDEILAAVPS GCVAITAIDG MAGIGKTTIA VRAAHRLAAR FPDAQLFVDL HSYTAGVEPR
TPSDALLALL TALGVPAQDI PDGLDARAAR WRAEMAHRKA LVVLDNAGST SQVRPLLPGT
GLVLVTSRRR LVDLDAAHTI SLDVLSEADS LNLLASIIGR AKLDQDVDSA REIVRLCGYL
PLAVRIVGAR WRTRPAWSAQ DLTRRLTGQR LSELTAGERS VADAFTLSYQ QLTPEQQRLF
RRLGLHTGED FDAYLAAAVV GTTRAEAERL LEELLDAHLV QQKENGRYRF HDLLADHAKA
SVEEDERVEA VTRVLDHYLH NAAASAQKIA PGRPQIHSAA TYVPVDPPLF ATPVEALAWQ
ETERSNLRAA VYLAAYEGYY QHAWQLPHHF AHFLLLRGSG RERVEVQSVA LAAARHLGDL
KARAEALRGL GSAYKDDNNP KAEEHLREAL GLMRQIGDLR GEASTLGLLG MIARERREYD
KAMLYFERGV VLMRHVGAQT GEANALHNIG IVHAERGETG QALAHLQEAV TLLEAHGDVR
ASAMTLHDMA HVHFDAFNDE ESLNFSERSL AAYRESGDRR GEALALADFA YWRYAMGDLA
AAGRTAREVG RLCRAYMILP DDHAVLAAME DVRDHFGQVA LLVSLSLDAH AAGRLSEALG
HVRRCLAVVR STSQWWSENR LLGQLSTLHL ALGDRDAAVR YGEKAVTAAE QLGQPRAVAV
AKQALATASA PAPPA
//
