ID   A0A1I6FAV8_9PSEU        Unreviewed;       903 AA.
AC   A0A1I6FAV8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=DNA-binding transcriptional activator of the SARP family {ECO:0000313|EMBL:SFR26907.1};
GN   ORFNames=SAMN04488564_110231 {ECO:0000313|EMBL:SFR26907.1};
OS   Lentzea waywayandensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=84724 {ECO:0000313|EMBL:SFR26907.1, ECO:0000313|Proteomes:UP000198583};
RN   [1] {ECO:0000313|EMBL:SFR26907.1, ECO:0000313|Proteomes:UP000198583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44232 {ECO:0000313|EMBL:SFR26907.1,
RC   ECO:0000313|Proteomes:UP000198583};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC       {ECO:0000256|ARBA:ARBA00005820}.
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DR   EMBL; FOYL01000010; SFR26907.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6FAV8; -.
DR   STRING; 84724.SAMN04488564_110231; -.
DR   OrthoDB; 3275754at2; -.
DR   Proteomes; UP000198583; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd15831; BTAD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR   PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000313|EMBL:SFR26907.1}.
FT   DOMAIN          17..92
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|SMART:SM00862"
FT   DOMAIN          99..229
FT                   /note="Bacterial transcriptional activator"
FT                   /evidence="ECO:0000259|SMART:SM01043"
SQ   SEQUENCE   903 AA;  99816 MW;  DBF2A7EBC08B8E0F CRC64;
     MTAEYRVLGP LEVLLDGEPV VVPAGRGRVL LATLLLRANE FVSVDELVER VWDGEPPALD
     RAHKTLQTVV LRLRQSLGAA NCVRTSSRGY TAEVAPGQLD LARFRELAAQ GDHRAALELW
     RGPVLGNVTS ESLHREDVPR LVEEQVVTLE RRIDEDLARA ADVLVPELWS LVRQHPLREV
     FWAQLMLALH RAGRQAEALS AYQEIRKRLA DELGVDPGRR LREAHEQVLS GEVPASPVVP
     RQLPPAYPHF AGREPELARL TEMVRVRPDE PVLISAINGI GGVGKTALAV QWAHRVADRF
     PDGQLHVNLR GFDLRAEPLD PIAVARDFLV GLGVPANELP TSDEAVIAEY RSLLARRRVL
     VVLDNARDVD QVRPLLPGGA GNLVLITSRN RLSGLVAREG AQPVSLDVMD EQAATDLLTE
     RIGAARIAAE PDAVARLVKR CAGLPLALGI VAARAAYGDP LTALADELEK ERLDALDIDD
     PTTGVRHVFS WSLRSVSEDA ARVFVMLGRH PGPEFTVEAA ASLAAVSGTE ARRALAELVG
     SSLVTRTSIG RYLLHDLLRD YAAERFGELS QERQAEAQQR MFDHYLHSSL KANRWTESRA
     VWTPLAPPSP AAVIAPVPDV QAAKDWFRTE QSVLLGMLTE MVTAGADDLV WRLAYTLHLP
     LLREGLLVEG EEAELLALAA AQRRDDVFGR QRLHRALGGI YIAKRELPKA EHHLRSALRC
     EEEMDNVDGQ VDVSRGLAHV YEELGHHDRS LEVLSRLHPR IAELNVYQRG YYLAALARAH
     QQVGERERAI ELCMEAEASF ALDDGPKKMP HANNAETLGD IYVELGRYAE AVESYRLSVD
     RMRAMHHTYY LGEGLFRLAR TQIAAGEPEA AREHLVEALS IYEKLHHRGT EEARALLASV
     INV
//