ID   A0A1I6FBY2_9PSEU        Unreviewed;      1288 AA.
AC   A0A1I6FBY2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:SFR27464.1};
GN   ORFNames=SAMN04488564_11163 {ECO:0000313|EMBL:SFR27464.1};
OS   Lentzea waywayandensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=84724 {ECO:0000313|EMBL:SFR27464.1, ECO:0000313|Proteomes:UP000198583};
RN   [1] {ECO:0000313|EMBL:SFR27464.1, ECO:0000313|Proteomes:UP000198583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44232 {ECO:0000313|EMBL:SFR27464.1,
RC   ECO:0000313|Proteomes:UP000198583};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOYL01000011; SFR27464.1; -; Genomic_DNA.
DR   STRING; 84724.SAMN04488564_11163; -.
DR   OrthoDB; 9805617at2; -.
DR   Proteomes; UP000198583; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd17989; DEXHc_HrpA; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:SFR27464.1};
KW   Hydrolase {ECO:0000313|EMBL:SFR27464.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          83..246
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          268..435
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1288 AA;  145743 MW;  832DD2D84DBB48B4 CRC64;
     MDTPHAELHK RLPELMPRDQ RRLARRLDGA RKVKDPLARR KITEEIAALI DEAALKVALR
     RESVPKITYP AELPVSQHKD EIKELIAHHQ VVIVAGETGS GKTTQLPKIC LELGRGVTGQ
     IGHTQPRRIA ARTVAERVAE ELGTKLGDTI GYKVRFTDQS GDETLVKLMT DGILLAEIQT
     DRTLSRYDTI IIDEAHERSL NVDFLLGYLK QLLPQRPDLK VVITSATIDP QRFSAHFENA
     PVIEVSGRTY PVETRYRPLE EDDDQTQGII NAVRELQAEG PGDVLVFLSG EREIRDTADA
     LKQEDLRNTE ILPLYARLSV GEQHRVFQRH TGRRIVLATN VAETSLTVPG IKYVVDPGNA
     RISRYSHRLK VQRLPIEPIS QASANQRKGR CGRVSEGICI RLYAEEDFEA RPEFTDAEIL
     RTNLASVILQ MTNIGLGDVA RFPFIDPPDS RNINDGIGLL QELGAINAAE KKLTPTGRKL
     AALPVDPRLG RMVLEADTTG CLREVMIIAA ALSIQDPRER PADQQEAATQ QHARFVDKES
     DFTTFLNLWE YLKEQQKELS GNQFRKRCKA EFLNYLRVRE WQDIYLQLRQ VAKQIGMHVN
     DQPGDPRNIH IALLSGLLSH IGVKDVLKKQ APGEKRRPLT EFLGARNAKF AIFPGSALAK
     KPPQWVMAAE LVETSRLWGR IVAKIEPEWA ERLGEHVVKR QYSEPHWESK RGSVVALEKV
     TLYGVPIVAG RKVSYGRIDP ELSRELFIRH ALVQGEWTTH HRFFHTNRAM LEEVGELENR
     ARRRDIVVDE ETLYEFYDKR VAPEVVSARH FDSWWKKQKD KNQLTFTKDM LVNDRADVTP
     DAYPDQWRQG ELTLPLSYHF EPGTKNDGVT VQLPLPALTT LDDDAFSWQI PGLRHDLVVA
     LIRSLPKPIR RNFVPVPDVA TAVLARIKPE ETSLLYGVER ELKALTGVTV HREDWQFDAV
     PDHLKLTFQV VDEHNRTLAE GKDIAALKEK LRDEVRESLS QAAGHLERTG LTTWDFDALP
     QTIEQRQSGI TVTAYPSLLD QGETVAIKVL DTPGRQAYAH RRGVRRLLLL GVNSPVKHLQ
     RHLDNAAKLA LTRNPHGSVA ALLSDCIMAA VDRLMGEPAW NAKSYAAQLK KVQAALNDTT
     WVAVQEVRKV LEAAHDAELK LSGLKGAPDS AADIRAHLNS LVYKGFVTHT GYDRLPDLVR
     YLKGISRRIE KLPENPRRDL DWTDKIHQVH AEYRELRAQT PADEPAPELD EIRWMIEELR
     LSYFAQTIPT RYSVSDKRIY KALDAVPL
//