ID   A0A1I6FDD1_9PSEU        Unreviewed;       353 AA.
AC   A0A1I6FDD1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Fatty acid desaturase {ECO:0000313|EMBL:SFR27920.1};
GN   ORFNames=SAMN04488564_11231 {ECO:0000313|EMBL:SFR27920.1};
OS   Lentzea waywayandensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=84724 {ECO:0000313|EMBL:SFR27920.1, ECO:0000313|Proteomes:UP000198583};
RN   [1] {ECO:0000313|EMBL:SFR27920.1, ECO:0000313|Proteomes:UP000198583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44232 {ECO:0000313|EMBL:SFR27920.1,
RC   ECO:0000313|Proteomes:UP000198583};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00009295}.
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DR   EMBL; FOYL01000012; SFR27920.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6FDD1; -.
DR   STRING; 84724.SAMN04488564_11231; -.
DR   OrthoDB; 104711at2; -.
DR   Proteomes; UP000198583; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:UniProt.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR   CDD; cd03506; Delta6-FADS-like; 1.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR19353:SF19; DELTA(5) FATTY ACID DESATURASE C-RELATED; 1.
DR   PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
DR   PIRSF; PIRSF015921; FA_sphinglp_des; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        66..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        165..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        206..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          64..321
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
SQ   SEQUENCE   353 AA;  39397 MW;  C262DF5BE7F4945B CRC64;
     MTTTHTAPTS TAERQPGSDF ARLTRELKAA GLLDRRRGYY LLRMAINALL LAAIAVAFVW
     LGDSWWQVIT AVALAVASTQ LAFIGHDAGH RQIFRSHRNN NVVGHLHGSL TGISYQWWVA
     KHNRHHANPN HEDQDPDIEI HALAFSRAQA TTKRGVYRWI TRNQAFLFFP LLLAEAAVLR
     ISGLVALCRK ELRNPWREAA LQLLPLAAYL AAAFIVLSPL KALVFIAVHQ GLMGVYLGCS
     FAPNHKGMPI IAEGQRLDHL HKQVLTSRNV TGGRWVDALF GGLNHQIEHH LYPHMPRPNL
     RRAQPVVEDF CARHGIPYSK TTMVRSYAEV LRHLHDAGAP LRQQAGRATT SAT
//