ID A0A1I6FEJ0_9PSEU Unreviewed; 431 AA.
AC A0A1I6FEJ0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Amino acid/polyamine/organocation transporter, APC superfamily {ECO:0000313|EMBL:SFR28370.1};
GN ORFNames=SAMN04488564_113218 {ECO:0000313|EMBL:SFR28370.1};
OS Lentzea waywayandensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=84724 {ECO:0000313|EMBL:SFR28370.1, ECO:0000313|Proteomes:UP000198583};
RN [1] {ECO:0000313|EMBL:SFR28370.1, ECO:0000313|Proteomes:UP000198583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44232 {ECO:0000313|EMBL:SFR28370.1,
RC ECO:0000313|Proteomes:UP000198583};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC {ECO:0000256|ARBA:ARBA00008583}.
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DR EMBL; FOYL01000013; SFR28370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6FEJ0; -.
DR STRING; 84724.SAMN04488564_113218; -.
DR Proteomes; UP000198583; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR PANTHER; PTHR43495; GABA PERMEASE; 1.
DR PANTHER; PTHR43495:SF5; GAMMA-AMINOBUTYRIC ACID PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..399
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 431 AA; 44998 MW; 901D8D5911A61E83 CRC64;
MIALGGVIGA GLFVGTGAGI ALAGPAVLIS FGLAGILALL VLRMLGEMAA EHPSGGAFSV
HAEKAIGPWA GFTVGWTYWA AVGVVLAVEA TGAAKIASGW VPAVPQWAWV LIFMSALTAV
NLANVRNFGE FEFWFAGLKV AAIVLFLLLG AAAIVGLLPN VDSPGTQNLH DFLPHGWGGV
IAGFMAVVFA FGGLEVVTIA AADAADPKHA IKKAVRTSMT RLLVFYLGSM AVVVTLLPWN
DSEVGASPYV AVLNRLGIPA AGQIMNVVIF VALLSAINAT LYGAARMLSS LAERGEAPKA
LLAKTNGVPR NAVLASTAFG FFSVLLNYLW PDTVFLLLLN AVGSALLVVW GFVAISQIRL
RRTYENPAVP MWGYPYLSWV ALAAIAGIIV LMLSDEQARG QILSTGVLVA VIAAVALSRS
ALRRRSLLDR T
//
