ID A0A1I6FHG8_9PSEU Unreviewed; 999 AA.
AC A0A1I6FHG8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ribonuclease E {ECO:0000313|EMBL:SFR29237.1};
GN ORFNames=SAMN04488564_11835 {ECO:0000313|EMBL:SFR29237.1};
OS Lentzea waywayandensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Lentzea.
OX NCBI_TaxID=84724 {ECO:0000313|EMBL:SFR29237.1, ECO:0000313|Proteomes:UP000198583};
RN [1] {ECO:0000313|EMBL:SFR29237.1, ECO:0000313|Proteomes:UP000198583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44232 {ECO:0000313|EMBL:SFR29237.1,
RC ECO:0000313|Proteomes:UP000198583};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOYL01000018; SFR29237.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6FHG8; -.
DR STRING; 84724.SAMN04488564_11835; -.
DR OrthoDB; 9804278at2; -.
DR Proteomes; UP000198583; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 1.10.10.2480; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR006847; IF2_N.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF04760; IF2_N; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 357..434
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 123..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 731..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 937..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 974..999
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..166
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..221
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..303
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..759
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 999 AA; 108332 MW; C90559FCB07F853D CRC64;
MSNKDKPAGV TGGQGVVAAR PELADLPDKL RVHALAKLLD VSSKDVMTAL ADLGEVPKSA
QSSVSRDVAL KVAETLVDWD DVVTGEVTED YEAPAIPAFE APALAPIFAA PSAVFLPPAP
IERPKAPPSP FVVEEEPVAE EKSVGEIAAD ELEAAEAAET DAEADGDDES DSRRRRRRGR
RGRGRGKGTD AEGGEETDEA AAETDASEPA ESDDAAEAED EGDESSTRRR RRRRRRKTGA
EDEVTSEDDP PNTVVHVRET RDARDDKADS EAAQSEVRSI RGSTRLEAKR QRRRDGREAG
RRRAPVLTEA EFLARREAVA RTMVVRERGD RTQIGVLEDG VLVEHFVTSS GSGSIVGNVY
LGRVQNVLPS MEAAFIDIGR GRNAVLYAGE VDWDAAGLEG KSRKIEQALS SGDSVLVQVT
KDPVGHKGAR LTTQISLPGR FLVYVPGGGA TGISRKLPDN ERKRLKDILK RVVPEDAGVI
IRTASEGIAE EELGRDVTRL QAQWKVIKEK SDSTSTKAPT LLYEEPDLLV KVVRDLFTED
FAQLVVQGDE AWEVIDSYVR HVAPDLQDRL KKHVGNNDAF VEYRIDEQLM KALDRKVWLP
SGGYLIIDRT EAMTVIDVNT GKFTGSGGNL EETVTRNNLE SAEEIVRQLR LRDIGGIIVI
DFIDMVLESN RDLVLRRLTE CLGRDRTRHQ VAEVTSLGLV QMTRKRVGTG LLEAFSQTCE
HCRGRGVVVS TEPVHSHGGG NGGGQQQSQP QQQSGGRKSR RNKGGGEQAA DTPEIVEASV
EAPEAPVEPE VIELGEPEDT SEDVVAADQE HEAHGRRRRR RRGRDKEPQA VVDAVVVEEQ
ALNGHVPHEV AEDPEPVELE PVVTDAEPEV IEEAAEELVE PVVEEAPVEV ARPLVTGRIG
AQRPVLVVEP EQEPVAAPQP VSAPEPVAVA PVAAVEPPAA RPRRRAAKRA AGAPAAEAPA
PIVVEVPKQP EVQMPAPVVT TTRRRRAVSR PAGPPVQED
//
