ID A0A1I6FRW9_9RHOB Unreviewed; 261 AA.
AC A0A1I6FRW9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=3-hydroxyisobutyrate dehydrogenase {ECO:0000313|EMBL:SFR32537.1};
GN ORFNames=SAMN04488005_0327 {ECO:0000313|EMBL:SFR32537.1};
OS Yoonia tamlensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Yoonia.
OX NCBI_TaxID=390270 {ECO:0000313|EMBL:SFR32537.1, ECO:0000313|Proteomes:UP000199478};
RN [1] {ECO:0000313|Proteomes:UP000199478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26879 {ECO:0000313|Proteomes:UP000199478};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOYP01000001; SFR32537.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6FRW9; -.
DR STRING; 390270.SAMN04488005_0327; -.
DR OrthoDB; 9812907at2; -.
DR Proteomes; UP000199478; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000199478}.
FT DOMAIN 4..147
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 153..246
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 159
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 261 AA; 27188 MW; 15C9A65019426D5A CRC64;
MSDKVGVAGC GRMGGPMLAN LQKAGFAAFG YDPNPAAGVG TDIDAFCAGL NTLITVVRDA
AETDALLFDD QAVVSRAKDL HRIVICSTLS PNYVKSLRAR VPDHITLIDA PMSGAQVRAR
AGTLTFMVGG DPAPILPLLQ AMGDAIHPMG AYGAGMTGKV LNNLLAASHT AMTRLVLDWG
DAQGMDETTL LALIGTASGQ NWLASGFDEI EFARDGFSND NSIGILAKDV GAALDIAPDG
QTALPEAVQN AIRQLQPRRK T
//
