ID   A0A1I6FW46_9FLAO        Unreviewed;       529 AA.
AC   A0A1I6FW46;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=TIR domain-containing protein {ECO:0000313|EMBL:SFR34163.1};
GN   ORFNames=SAMN04490243_0788 {ECO:0000313|EMBL:SFR34163.1};
OS   Robiginitalea myxolifaciens.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Robiginitalea.
OX   NCBI_TaxID=400055 {ECO:0000313|EMBL:SFR34163.1, ECO:0000313|Proteomes:UP000199534};
RN   [1] {ECO:0000313|EMBL:SFR34163.1, ECO:0000313|Proteomes:UP000199534}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21019 {ECO:0000313|EMBL:SFR34163.1,
RC   ECO:0000313|Proteomes:UP000199534};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOYQ01000001; SFR34163.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6FW46; -.
DR   STRING; 400055.SAMN04490243_0788; -.
DR   OrthoDB; 783026at2; -.
DR   Proteomes; UP000199534; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199534}.
FT   DOMAIN          7..166
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   REGION          187..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   529 AA;  59438 MW;  FA014C6CA5C54C6B CRC64;
     MAFVPGYEYD VFISYAHVDN ICFPDQGDGW IKQFYQNLNL MLAKRSGRLD SIKIWWDTKK
     LDGSVLFDDS IAAGIEKAAI MICLNSPGYK ASKYCAQELD LFHKKAAGEP GGLKAGQQTR
     IFHVLLNNIP HTDWPDELQG STGFPFHDGE DQHDFGDTVE TTSAQFKAQM RHLKDAVFRA
     LETMQKEAGS ASAPTKPKKL AGKKPSTAKA SAAEKAPATN TESVASDEGF TIFMSEVPDT
     LRSPRKRIIS ELEKNGYQVL AGIPPPDAKE ELQKETEAAL QTSGLAVNLL DIYPGREVVD
     APDVWYPQFQ TELSLKTEVD QLIWIPADSD FAEIEEGEYR NFLTKLEEGE LTKKRYEFIR
     GSKSSLARQI MDYAEVIKSK SAAPIEDDGE IPVLLDAHEN DHLYALDLGR SLLQNQFRPF
     INPQEDDPRK NLDLLGKRMS QVRKLIFLYG NVSKDWVLER MNAALQLILT NNYPIEDFFI
     YMAPPHKEAG DISINQRLLK VNVIDNSNDP TLTEQAVDRF LKELKLQAG
//