ID A0A1I6FXT8_9FLAO Unreviewed; 1376 AA.
AC A0A1I6FXT8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:SFR34765.1};
GN ORFNames=SAMN04490243_0883 {ECO:0000313|EMBL:SFR34765.1};
OS Robiginitalea myxolifaciens.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Robiginitalea.
OX NCBI_TaxID=400055 {ECO:0000313|EMBL:SFR34765.1, ECO:0000313|Proteomes:UP000199534};
RN [1] {ECO:0000313|EMBL:SFR34765.1, ECO:0000313|Proteomes:UP000199534}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21019 {ECO:0000313|EMBL:SFR34765.1,
RC ECO:0000313|Proteomes:UP000199534};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; FOYQ01000001; SFR34765.1; -; Genomic_DNA.
DR STRING; 400055.SAMN04490243_0883; -.
DR OrthoDB; 4317020at2; -.
DR Proteomes; UP000199534; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR018317; QueC.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF06508; QueC; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000199534}.
FT DOMAIN 1292..1367
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1376 AA; 153589 MW; 2C1F0FDB93B75CA2 CRC64;
MTNPTPTYYP LTPSQKQIWT GQLLFPDSPL YHVPYLFKFN GAINPEVLQN AFQELVNCTD
ILRIVIGEGN EGLEQQVLPT YTFALERIEM GSADFEKSVE KWALDRSNLP LATNKPLFDA
AILENRESGF VLYLNLHHVI TDAITASLLF ERLSGIYDNL IQGKPALTEL ELPQYRDCIT
PLVAQGESHA QDATIRYWQD KQTRLPVFPQ LGSPGKPGLD TKTTRVAIPL GSERFKKITE
LLGQKGFATF TRQMSLTNFF TSVLTAYLYR VSGQRAFTIG TPVHNRYTHQ EKKTPGLFIG
VYPLINKIDP ERSFRELAAS NYQELAETLG HCGSGIASTA ISRNINCIVN YLPATFTNFG
GMPVETKWIH PGYSDPMHYI RLHLTEFAAD EPLELSADLS SDVFTAEQIN SFPQNFLDIL
DALVAQPDET LGKISRVNPE MEALFLENFD KTALAPEPKT FLELFQEQVQ NQPENTAFTL
NDSAVSYAEY QQKANTWAAA LKASGCQRGD TVALQLGRTE DYMFALLAIM QLGGIFIPMP
SDLPAERRDY ILVDSGCSFI LSRSTFTTPE GIQVLTPEDL NRAEPNETPE FNSLGTADRA
YIIYTSGSTG NPKGVAIQHG ALGNYLQWAR DRYAIDAQTV MPLFTSLGFD LTLTSTLLPL
VAGGRVSLVP EPAIGPDLAA LRIWSMEDIT AIKLTPSHLR LAGDRNPELP NLKTLIVGGE
NFQTALAEQA TANFGHGVAI YNEYGPTEAT IGCIVHRYAP TQSASVPIGS TIAGMGAFIL
DEHMQLTPPG VPGEIYLSGA GLSTGYINRA ELNQERFVFH PESGQRLYRT GDVGIWNTDG
VMEYHGRNDE QVKVNGHRVE LQEIEAVLAQ FPSLEGAAVS LDTINKPLQE SEANCRECGL
PSEYPSADFD ENNVCHLCRS FADYQNEVAS YFKTEDDLYQ QIRSGTNSDN KYDCLSLLSG
GKDSTYVLAK LIDMGFKVLA FTLDNGYISE QAKANIDKIV TALGVDHVYG STEHMNEIFV
DSLERHANVC NGCFKTIYTL STQIALEHEI PFIVTGLSRG QFFETRLAEE TFMDFRDSGK
SIDDIILEAR KLYHQEDDAI KQLLETEIFN DANNFEKVQF IDFYRYTDVS LSELLRFLKE
KIGWERPTDT GRSTNCLINQ LGIYVHKKKK GYSNYAFPYS WDVRLGHKTR EESLDEINEA
LDEEEIRKMM GEIGYFEDLE PTDQLVAYVA GDNLPNSQEL RAYLAGKLPA YMIPTTFKKV
EALPLTPNGK VDKKALQELN PLQLGAATKY VAPRNDLEEL LAEHWGEVLQ LEKVGIHDNF
IDLGGHSLAA IRITGRINRE LTLELPLSKI FEHPTVAEYG VYLENKLEEL MALDDD
//
