ID A0A1I6GRB0_9GAMM Unreviewed; 1148 AA.
AC A0A1I6GRB0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN04488070_1100 {ECO:0000313|EMBL:SFR44587.1};
OS Pseudidiomarina maritima.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Idiomarinaceae; Pseudidiomarina.
OX NCBI_TaxID=519453 {ECO:0000313|EMBL:SFR44587.1, ECO:0000313|Proteomes:UP000199424};
RN [1] {ECO:0000313|Proteomes:UP000199424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7285 {ECO:0000313|Proteomes:UP000199424};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC family. {ECO:0000256|ARBA:ARBA00006434}.
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DR EMBL; FOYU01000001; SFR44587.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6GRB0; -.
DR Proteomes; UP000199424; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd10322; SLC5sbd; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.20.1730.10; Sodium/glucose cotransporter; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038377; Na/Glc_symporter_sf.
DR InterPro; IPR001734; Na/solute_symporter.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43047:SF9; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12860; PAS_7; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 35..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 797..1008
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1029..1146
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 728..790
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1079
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1148 AA; 127725 MW; 6E5F1F0C191CB2EB CRC64;
MTLLLILASL AYIALLFAVA HWGDKPNSLA NKISYKPIIY SMSLAIYCTS WTYYGAVGNA
ATDGWAYIPI LLGPFLLFIF ALPLLEKLVS VSKQQNITSI ADFIASRYGK RQRLALFVTL
IAALATIPYI ALQLKAVGLT FVVLTENTSA LTQFSINELV AAGIMAVFAM LFGTRHIEVT
EYRNGMILAI AFESAVKLLA LLAAAVFAYF LFNDVSPVSM WEQVTTPSSK AWSWEALTEF
DFIVQTFMAA GVILCLPRQF HVAVVDNVNV NHLKTARWGF PLYLVLVAVA IVPIALSGGL
FFGNGIDGDT YALRLPLLHD QTWLAVFIFI GGFSAATAMV IIASVTLSTM VTNDVIMPVI
LQRRSRFPTS FQKRLLFIRR VAIAIILLLS YLCYYFWAAG TGLVSIGLLA FSVVLQLLPA
VLGGLYWRRG HARGVYVGLG TGLIAWLFAV AVPMYLPHDS TDTSIITQGT VISLAVNTAF
YFVFSLLAQP RLIDRIQATA FVKPRTRVQE HTVGRHHQAT NGDMMLLLQT FVGEQRTAQL
LDYFAEAQGN DSSHTNKEDV ASREFIDYVE RVLTGVLGAA TARSLVEAAL RDRRLHLEEV
VHFFDDTTQA LQTQQAILFS SLENLAQGIS VVDADLRLVA WNKRYLDLFD YPDGMVKPGQ
PIATLIRYNA ERGECGPGEI DELVAKRLKH MQVGSPHRFI RRRGDGRVIE MVGNPLPNGG
FVTSFTDITE HVETQQALEE ANIDLEQRIN VRQKKIREIN NELTEEIERR RKVEVELKKA
TQQAEEANAS KTRFLALASH DILQPLNAAR LYLSAMDENN LNHNNLQLVS KLDTALASTE
HLLSTLLQIA KMDQGALQPS FRHVRLSTIL EPLIHEYGVL AEQRGITLKT HLHDGVVYTD
PTYLRRIIQN FLSNAVKYNR DQGKVLLAVR KRGEHLLIAV YDTGPGITAQ QRHRIFDAFY
RGSQTRVEGV GLGLSVAKRM SEQLHCELRL KTVEGSGSCF SVQVPLGNPS QVYEKPQQAN
TADVNRGMQV VCVDDDQENL SALRALLEKW GCTVETFTSS ATALEYASTH ERPDGILLDY
QLGDDEHDGL SLARALRHYW GDTLSGALVT AMRDDSVRKQ AREQNLHFLA KPVKPAALKS
LLKYLERQ
//
