ID A0A1I6HH88_9RHOB Unreviewed; 1115 AA.
AC A0A1I6HH88;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN ORFNames=SAMN04488005_2693 {ECO:0000313|EMBL:SFR53748.1};
OS Yoonia tamlensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Yoonia.
OX NCBI_TaxID=390270 {ECO:0000313|EMBL:SFR53748.1, ECO:0000313|Proteomes:UP000199478};
RN [1] {ECO:0000313|Proteomes:UP000199478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26879 {ECO:0000313|Proteomes:UP000199478};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; FOYP01000002; SFR53748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6HH88; -.
DR STRING; 390270.SAMN04488005_2693; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000199478; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR014151; DNA_helicase_AddA.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR02784; addA_alphas; 1.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000199478}.
FT DOMAIN 3..478
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 497..781
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 24..31
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1115 AA; 123200 MW; 61C2EE340A20F2BD CRC64;
MKRDPATQRQ VEAANPQTST WLSANAGSGK TRVLTDRVAR LLLEKVSPQN ILCLTYTKAA
AAEMQNRLFK RLGAWAMMAD ADLRADLQTL GVDHAVDDEQ LRAARTLFAR AIETPGGLKI
QTIHSFCAGI LRRFPLEAQV SPQFREMEDR AAELLRAEVM DELLTGDHAA TVNNVLHHFT
GAELSKLTAE VAQKRDAFAH EMPRAELCAL LGIDPSLTAD TLVAQVLNQS ALDSIHQLAA
ACRKGSVTDA KAAAQLDKIS KTAPATLNDL ALLEGVFLFG ATATQPFGAK IGKFPTKATR
EANPELMDDI EPVMLATGDA REDRLSLMAL DRTLAIYRFG AVFIPAYERR KLMMGALDFD
DLIRKAKALL TDRDVAQWVL FRLDGGIDHV LVDEAQDTSP TQWAVIEQLT HEFASGEGAH
PDRTRTVFVV GDKKQSIYSF QGADPDAFDA MKTHFNSTHI AAGKAFEVTS LEHSFRSSTA
ILAVVDATFT GDRTAGMDDH LSHQAFKQNM PGRVDLWPVI EKSETEDPRN WFDPVDLPSD
TDHNVLLANR VAAQIKRMIA EETLPDEIDN ADSYRRRPIT EGDFLILVQR RSELFSEIIR
ACKSAGLKIA GADRLRVGAE LAVKDLAALL NFLALPEDDL SLASALRSPL FNLSEQDLFT
LAHHRPAKGF LWTALRGSQH TNIYAVIDDL LDQADFLRPY DLIERILTRH DGRRKLLGRL
GPEAEDGIDA LLSQALAYES TGVPSLTGFL TWMETDDLEV KRQMDSQGDQ IRVMTVHGSK
GLEAPIVILP DTAKRRVDVR DELLPVGDHV VWKTPSQGSA TVMQDIREDF IAKQTRERMR
LLYVAMTRAE KWLIVAAAGD VGDGDESWYN IVADGMAAQG DTRVQIDDME ARRVAHLDWN
AGTLHRTDPK AAPDFTPPAF GPVPVAKTKT TISPSAFEGA KIMPGDPANL DIEDAMERGT
KIHRLLEFLP QYAAHERRAI GLRVLNDGDA DLVEEVIQLL ENPDLAALWH PDALTEIDIT
AELEGIGRIH GTIDRLIITD TEILAIDYKS NRIVPEKPEQ TPLGVLRQMA AYFAALRQIY
PDRVIRMGVL WTATAHFAEL PEDLLHETLN GLAIP
//
