ID A0A1I6HMX8_9GAMM Unreviewed; 702 AA.
AC A0A1I6HMX8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Flagellar biosynthesis protein FlhF {ECO:0000256|ARBA:ARBA00014919};
DE AltName: Full=Flagella-associated GTP-binding protein {ECO:0000256|ARBA:ARBA00030866};
GN ORFNames=SAMN04488070_1953 {ECO:0000313|EMBL:SFR55748.1};
OS Pseudidiomarina maritima.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Idiomarinaceae; Pseudidiomarina.
OX NCBI_TaxID=519453 {ECO:0000313|EMBL:SFR55748.1, ECO:0000313|Proteomes:UP000199424};
RN [1] {ECO:0000313|Proteomes:UP000199424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7285 {ECO:0000313|Proteomes:UP000199424};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Necessary for flagellar biosynthesis. May be involved in
CC translocation of the flagellum. {ECO:0000256|ARBA:ARBA00025337}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the GTP-binding SRP family.
CC {ECO:0000256|ARBA:ARBA00008531}.
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DR EMBL; FOYU01000003; SFR55748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6HMX8; -.
DR Proteomes; UP000199424; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR CDD; cd17873; FlhF; 1.
DR Gene3D; 1.20.120.1380; Flagellar FlhF biosynthesis protein, N domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR020006; FlhF.
DR InterPro; IPR047040; FlhF__GTPase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000897; SRP54_GTPase_dom.
DR NCBIfam; TIGR03499; FlhF; 1.
DR PANTHER; PTHR43134:SF3; FLAGELLAR BIOSYNTHESIS PROTEIN FLHF; 1.
DR PANTHER; PTHR43134; SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA; 1.
DR Pfam; PF00448; SRP54; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00962; SRP54; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|ARBA:ARBA00022795};
KW Bacterial flagellum protein export {ECO:0000256|ARBA:ARBA00023225};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000313|EMBL:SFR55748.1};
KW Cilium {ECO:0000313|EMBL:SFR55748.1};
KW Flagellum {ECO:0000313|EMBL:SFR55748.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 162..412
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 163..363
FT /note="SRP54-type proteins GTP-binding"
FT /evidence="ECO:0000259|SMART:SM00962"
SQ SEQUENCE 702 AA; 77885 MW; 48F8FB08B521A3A3 CRC64;
MTIRRFRAAS HKDAMRKVRD ALGEDAVIVS SRKTAQGAEV FAISEADLAQ LQDADEVPSP
ASPDFSGIAQ QLLSDMQDMR AMLHQQQGEK APDDNRKRLY RQLRAGGYSD ALSRQLVALL
PSALNHSNKT YPEALKWLQQ QIVARISHQS EMRVNDWELL QHQGVMAFVG PTGVGKTTTT
AKLAANYVMQ HGNDSLLLVT TDSYRIGAQQ QLAIYAELLD VQMHALADGD TLDSLAEKMH
GKRLVLVDTV GMSQRDQRLA QKIAALGSAE HRDSTRLVLL LNAAAQQETL DEVARIYQRI
ARESDLIIHD CILTKLDETA RMGGVLDTVI RHKLTVQATA SGQRVPEDIR VPDIEQLVAD
SLTAEVSSSQ LAESEWEQAS ETLEPSQVFA HGHLIQSNMQ ALRQQIPHFD ELVQALKLKQ
LPDHWANTAF PDELNMIRWA APQPLQGWSH LTPHLGLNKR GLPLLPPVLH SAENPVLVDM
ALAPVQLFDY LPQPELLDIF SQHQTGWLAT LNLNHKVQFQ GQPFTVNGLV KKHGIPLSKH
TILYRGERRR LELTIAAAET EPSQQLVQVI YGELHGGPSK NPVQRRYWLA DGNCTAEQVV
ERTRAMLQLE EFARLTRLAW RSLGKYELDS RTQLGLAGAL AAVALHVEYH AAAQFAGLRG
ELLSISGKRG RVQGDKLLPA ILHVIHAYDS LVVAGREVEA QG
//
