ID   A0A1I6II88_9MICO        Unreviewed;       379 AA.
AC   A0A1I6II88;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Predicted naringenin-chalcone synthase {ECO:0000313|EMBL:SFR66381.1};
GN   ORFNames=SAMN05428970_0026 {ECO:0000313|EMBL:SFR66381.1};
OS   Agromyces sp. CF514.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Agromyces.
OX   NCBI_TaxID=1881031 {ECO:0000313|EMBL:SFR66381.1, ECO:0000313|Proteomes:UP000199174};
RN   [1] {ECO:0000313|EMBL:SFR66381.1, ECO:0000313|Proteomes:UP000199174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF514 {ECO:0000313|EMBL:SFR66381.1,
RC   ECO:0000313|Proteomes:UP000199174};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR   EMBL; FOZD01000001; SFR66381.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6II88; -.
DR   STRING; 1881031.SAMN05428970_0026; -.
DR   OrthoDB; 9786288at2; -.
DR   Proteomes; UP000199174; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
PE   3: Inferred from homology;
FT   DOMAIN          8..216
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          233..375
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        157
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   379 AA;  40306 MW;  A4CEF509D9DA52E5 CRC64;
     MAISLRGIST VVPATVLVQD AVRDVFAAQP GLNRLAQRIV TTSFNVSGIE RRHSVLEELT
     LEPRDEAPVF FDQKTGELLL PGTKARNEIY AREATRLYVE AGRAAIEATP GVEASDVTHV
     ITVSCTGFYA PGPDFMVARD LGLNAGVERY HLGFMGCYAS IPALRLARQL CEADAAAVVL
     VISVELCTLH LRSSNDPDTI VASSLFSDGA GSGIVSTRDP EPGERAFELD RFATRITPVG
     EGDMAWKIGD HGFEMVLSNA VPAIIDAHIT GALEPLFAPD AALAEALAND TSSEAIEHWA
     IHPGGRSILD KVEARLALTE EQLVPARETL RDYGNMSSAT VLFVLANILE SDAAAGDRVA
     AMAFGPGLTV ESALLTVRG
//