ID A0A1I6INM3_9MICO Unreviewed; 363 AA.
AC A0A1I6INM3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=SAMN05428970_0392 {ECO:0000313|EMBL:SFR68316.1};
OS Agromyces sp. CF514.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Agromyces.
OX NCBI_TaxID=1881031 {ECO:0000313|EMBL:SFR68316.1, ECO:0000313|Proteomes:UP000199174};
RN [1] {ECO:0000313|EMBL:SFR68316.1, ECO:0000313|Proteomes:UP000199174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF514 {ECO:0000313|EMBL:SFR68316.1,
RC ECO:0000313|Proteomes:UP000199174};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; FOZD01000001; SFR68316.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6INM3; -.
DR STRING; 1881031.SAMN05428970_0392; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000199174; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 13..351
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 363 AA; 38141 MW; 41350ADDD06A8686 CRC64;
MSDHISATVA DGVGHVTLNR PKALNALSYD MIVALAEVFD AWRDDSEVAV VVLDGAGDRG
FCAGGDIREL HGFATSGRAA EAQTFFRTEY RLNATIARYP KPVVAIMDGI TMGGGIGLAG
HASVRVVTER SRLAMPETRI GFTPDVGGTW LLASAPGELG VHLALNSRTM DAADAIHAGF
ADALVPSESL PHLLQALAER ADPGSPAEIV MLFDETPGPS PLAASRDWVD ACYSAPTVSG
IIERLRAFAA TPAGEGGADA AASAREQAAA AADELETLSP TALAVTLGAV RRARTLPRLE
DALEQEFRLV SWFLGQADLH EGIRAQVIDK DRTPAWRPGA LAELPADLFE SALSAPVDRG
VFD
//
