ID A0A1I6J708_9EURY Unreviewed; 591 AA.
AC A0A1I6J708;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Spermidine synthase {ECO:0000313|EMBL:SFR74749.1};
GN ORFNames=SAMN04487947_4138 {ECO:0000313|EMBL:SFR74749.1};
OS Halogeometricum rufum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Halogeometricum.
OX NCBI_TaxID=553469 {ECO:0000313|EMBL:SFR74749.1, ECO:0000313|Proteomes:UP000198531};
RN [1] {ECO:0000313|EMBL:SFR74749.1, ECO:0000313|Proteomes:UP000198531}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7736 {ECO:0000313|EMBL:SFR74749.1,
RC ECO:0000313|Proteomes:UP000198531};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867}.
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DR EMBL; FOYT01000006; SFR74749.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6J708; -.
DR STRING; 553469.SAMN04487947_4138; -.
DR OrthoDB; 10538at2157; -.
DR Proteomes; UP000198531; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43317:SF9; POLYAMINE AMINOPROPYLTRANSFERASE 2; 1.
DR PANTHER; PTHR43317; THERMOSPERMINE SYNTHASE ACAULIS5; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Polyamine biosynthesis {ECO:0000256|PROSITE-ProRule:PRU00354};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 280..535
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 449
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 591 AA; 65938 MW; 80A4DF8E69234572 CRC64;
MSQVTARTKT LTLLGVTFVV SFCSFAYEFV YSELLTVMYG GTVTQYVITV GLYFFSLGVG
AALSDDLSGD RPSNLFRTEV YLAVLAPAGF LLVVALNSVR IPQAVPSELL WVVARSPVVV
VGLLSGFELP LLTRMVEDEE GDTDALVPAW ASRATNLLHG GVVRVMGVFW HVERTTERRS
GLSLVLAMDY VGGLFGAVVY ARVLYPRLGL IPTIFVLALL NGVAALAFVA RFSGEWGLFR
GERRRLVGRE SATLLVVCLL VTASYGVAVY EHERVDETLS SLYLEQDVED EYAPGAMRAS
VVGQHTTTYQ HVVEYERTWT GVGENPHFAG ETERCLRLGT AVQLCDSWAD SYHSGLVDVP
MTRFDHDPET NVLVVGGGDY VAVDHLREYD VTVDQVDIDA EFMAYARNDS FLSKWHDDAY
EYDRLTTTVA DGYTYLRQTN ETYDLVLLDV PGATDDDLLK LYSTEFYGAI RDRLASDGVV
VTWTYAASAY GDHNKAFTNT VRDAGFTRYA PYWAWEDIDA DGDVERVERF YVLAPGDRPG
TNGTAFDVDR GDDYVRRHGD RYRDVRWREV PRYDGVEVNS IFDPNYDIIV D
//
