ID A0A1I6KFN9_9EURY Unreviewed; 596 AA.
AC A0A1I6KFN9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Oligopeptidase F. Metallo peptidase. MEROPS family M03B {ECO:0000313|EMBL:SFR89858.1};
GN ORFNames=SAMN05216559_0701 {ECO:0000313|EMBL:SFR89858.1};
OS Halomicrobium zhouii.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halomicrobium.
OX NCBI_TaxID=767519 {ECO:0000313|EMBL:SFR89858.1, ECO:0000313|Proteomes:UP000199062};
RN [1] {ECO:0000313|EMBL:SFR89858.1, ECO:0000313|Proteomes:UP000199062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10457 {ECO:0000313|EMBL:SFR89858.1,
RC ECO:0000313|Proteomes:UP000199062};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOZK01000001; SFR89858.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6KFN9; -.
DR STRING; 767519.SAMN05216559_0701; -.
DR OrthoDB; 275607at2157; -.
DR Proteomes; UP000199062; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09608; M3B_PepF; 1.
DR Gene3D; 1.10.1370.20; Oligoendopeptidase f, C-terminal domain; 1.
DR Gene3D; 1.20.140.70; Oligopeptidase f, N-terminal domain; 1.
DR Gene3D; 1.10.287.830; putative peptidase helix hairpin domain like; 1.
DR InterPro; IPR013647; OligopepF_N_dom.
DR InterPro; IPR042088; OligoPept_F_C.
DR InterPro; IPR045090; Pept_M3A_M3B.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR InterPro; IPR004438; Peptidase_M3B.
DR NCBIfam; TIGR00181; pepF; 1.
DR PANTHER; PTHR11804:SF79; MITOCHONDRIAL INTERMEDIATE PEPTIDASE; 1.
DR PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR Pfam; PF08439; Peptidase_M3_N; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000199062};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 116..183
FT /note="Oligopeptidase F N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08439"
FT DOMAIN 204..582
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
SQ SEQUENCE 596 AA; 68010 MW; 9732B036D7A35545 CRC64;
MSSVPERSEI AEEHKWDLES LFADDEAWEA AYEDAEELVA DLERYEGRAT DDAATLLETL
ETYEELMRTV ADVASYARMR KDEDTTRDRY QALTARSQSL SSDASSAASF LEPALQELTW
DDVEAMIDEE PALAEYEHYF DDVLRMKEHT RSAEVETLLA ELSEVTGAPG EVYNMLANAD
MEFPTVEDSD GEPQPITLNN FTTLQKNPDR EFRQRVYEAF YDEWGTVRNA VGAAYKNSVK
TDVKMAQARD YDTAREAALD GPNVPVEVYD NLVETVNDNL DKLHRHAELK RDAIGADELR
MWDLYVPVVQ EESPDVEYEQ ACEYVVDAMA PLGEAYQDRV ADGLESRWVD VYETANKQSG
AYSGGTYDSQ PFILMNYQDD VESMYTLAHE LGHSLHSEYT SEHQPYVYSG YEIFVAEVAS
TVNETLLTHH LLETVEDDRL RKHVLNEYLE RFRSTLYRQT MFAEFEHRAH EMDEAGEPLT
PDRLDDLYRD LKGTYYEPAA VDDRIAREWM RIPHFYRAFY VYQYATGISA AVALVDGILE
EGEPAAERYV DFLSNGSREY PLELLQGAGV DMASPEPVER AVSTYGDYLD ELSALV
//
