ID   A0A1I6LFZ1_9FIRM        Unreviewed;      1376 AA.
AC   A0A1I6LFZ1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Phosphopantetheine attachment site {ECO:0000313|EMBL:SFS02415.1};
GN   ORFNames=SAMN05661086_03273 {ECO:0000313|EMBL:SFS02415.1};
OS   Anaeromicropila populeti.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Anaeromicropila.
OX   NCBI_TaxID=37658 {ECO:0000313|EMBL:SFS02415.1, ECO:0000313|Proteomes:UP000199659};
RN   [1] {ECO:0000313|EMBL:SFS02415.1, ECO:0000313|Proteomes:UP000199659}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=743A {ECO:0000313|EMBL:SFS02415.1,
RC   ECO:0000313|Proteomes:UP000199659};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Antibiotic biosynthesis; bacillaene biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004789}.
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DR   EMBL; FOYZ01000016; SFS02415.1; -; Genomic_DNA.
DR   STRING; 37658.SAMN05661086_03273; -.
DR   OrthoDB; 9778383at2; -.
DR   Proteomes; UP000199659; Unassembled WGS sequence.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   CDD; cd00833; PKS; 1.
DR   Gene3D; 1.10.1240.100; -; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.30.70.3290; -; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR032821; PKS_assoc.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF16197; KAsynt_C_assoc; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS52004; KS3_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199659};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          592..669
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          688..1110
FT                   /note="Ketosynthase family 3 (KS3)"
FT                   /evidence="ECO:0000259|PROSITE:PS52004"
SQ   SEQUENCE   1376 AA;  154094 MW;  D73F4073E8B47D82 CRC64;
     MSEKAILYGK PLALPKEFHT LSEMILHISE KHPKKGLTYV NGSGQEDFIT YRELVNGARR
     YLNVFRKKGI EAGQVMILVI DEPKEFYYTF WACVFGGIIA APVTQPSSWE ENSTGLIKLK
     KIWNILNKPK VVIEERQVKG YEQLKGYSDF KGFEYITTTE LKSDEMAEIY KTDKDQVAFL
     QFSSGSTGIP KGVQLTSKNI LTNNLACIES MELTEDDVAV TWLPHTHDMG LFGQHFIPMA
     AGSNIVVFSP FTFIRSPYLF MKKITEHKGT WFCSPNFGYD WMVKKVTEKQ LETLDLSSLR
     ITLNGAEPIS TLVAKQFIEK FSKCGCKENV MFPSYGMAEA TVGAAMPKVG SVMGIEKISR
     SKLIQNNIAV SVTEDSGYDT VEFVHEGQPI AETSIRIVDK TGKVLEENEV GEIQIKGASV
     TSGYYNCKEL TEDTFVDGWL KTGDLGFITK GSLVVTGRIK DILFIRGQNY FAHDLEQTIY
     EAGMLQCGDL AFVGSFNSKL QEEELILFVK YRISQMKDFL QLRKSIKDRI SGELQLEVKH
     VIPIKSIPKT TSGKLQRFEL RKNYENGQYN ELISKIDDVA HNIEGSRKSI VMPENELEEF
     LVAAWSEILQ IPENTISVED SFFVLGGNSV KAYQLLDKIE TYKKCEYGFE LLALCKTIRQ
     ISEYIEKFSK KPDTNENGKS TTAYKKDSIA AAITGIGFRF PQAKTQQEFW EHLCEQKDCV
     AKVSDKRKGL AGTVQWNEWI GELEDIECFD ADFFEINHQE AVFMDPQQRL ILETAYEALE
     DAGLITDDSQ ERNVGVFSGI SANTYYQLVV KYVEQYGVEE VPAKTMVNNM SNIISAYISH
     QYNFTGPVMA LDTACSSFMA ALHYGVRGIK EGSLSGAVVA SSNILTTPIV SQLARKAGII
     SSTSHCKVFD QEADGSVLGE GVIVVYVEPY ENAVKENKNI YGIIRGTALN NDGYSLGIMA
     PNPKGQYEVI AAAYEDAGVH PDEIGYIEAH GTGTTIGDPI EVNALSKVFA KDKGIRSSKV
     GIGSVKTNLG HLLPASGGAG LIKVLLCLKN KKLVPSLHMD QVNPALQIEK SPFYIVRDVQ
     QWQVEGQNTR KAGISSFGLG GTNTHIVVEE GGSVPANQNI QKKQELLLLS GKTEDALSRR
     ISQMENMLKE ETEINLYDLC YTSNRYRRHY GFRAACLVTA EGVQIIAKGQ FLKERAAKIN
     IFIGDIINVE EHEKQEKLLL HWYSVIKAVM KSCESVISVH GIYSGQILAE VLQNTISLSA
     AIEIIRQKKW SEQIELEQKL WKKTDVILSF GISEQEIYTD YYSQSKKKIQ VIYVDPSVKE
     EKQEQLPSIL GKMYAKGAGF VWKSLYPDGT GRIIHLPAYP FEKKSYWIHN KKGDIK
//