ID   A0A1I6M304_9EURY        Unreviewed;       430 AA.
AC   A0A1I6M304;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE            EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN   ORFNames=SAMN05216559_3620 {ECO:0000313|EMBL:SFS09922.1};
OS   Halomicrobium zhouii.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Halomicrobium.
OX   NCBI_TaxID=767519 {ECO:0000313|EMBL:SFS09922.1, ECO:0000313|Proteomes:UP000199062};
RN   [1] {ECO:0000313|EMBL:SFS09922.1, ECO:0000313|Proteomes:UP000199062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.10457 {ECO:0000313|EMBL:SFS09922.1,
RC   ECO:0000313|Proteomes:UP000199062};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC         Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR   EMBL; FOZK01000004; SFS09922.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6M304; -.
DR   STRING; 767519.SAMN05216559_3620; -.
DR   OrthoDB; 8639at2157; -.
DR   Proteomes; UP000199062; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 1.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   PANTHER; PTHR10322; DNA POLYMERASE CATALYTIC SUBUNIT; 1.
DR   PANTHER; PTHR10322:SF23; DNA POLYMERASE DELTA CATALYTIC SUBUNIT; 1.
DR   Pfam; PF00136; DNA_pol_B; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199062}.
FT   DOMAIN          314..411
FT                   /note="DNA-directed DNA polymerase family B
FT                   multifunctional"
FT                   /evidence="ECO:0000259|Pfam:PF00136"
FT   REGION          407..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        407..422
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   430 AA;  47941 MW;  A50E74B6E8577347 CRC64;
     MPFTIVFLAD GRVLEWEATE GGAVVTERED YTPRFYVAPR DRDADNDLTP LRSLYDRHPD
     VAAAEVTARR PSFRRDDERV LAVDVDHIDR VTALARKARQ LAEYPVGDLA CFNVDFSREF
     RYCLETGVDP TPTTELSTLR LGVPLSETAG EAYDELAVDG ETVSGPPAAV LTAVQTAIDD
     HGLDVLVCST SDIVPTLYEM AETAGFDEFT LSRWPDVGYQ QLASRSTYAS YGQVGHSPAR
     YNVPGRAIVD ESNTYFYGET NLDGILDLVS RSKKPVQETA WASIGNVLTA IQICEAHDRD
     VLVPWNSWRH ERYKTMGTLH DADRGGFIFA PDVGLHDDVH ELDFSSLYPN IICTQNVSPD
     VIRCDCHRHC EDVPGLGYAI CDERGYLVDV LQPIIDDRDE IKAAIQREKQ RDAPDQERLE
     ELEAVPLLGS
//