ID   A0A1I6M702_9SPHN        Unreviewed;       573 AA.
AC   A0A1I6M702;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Cell division protein FtsI (Penicillin-binding protein 3) {ECO:0000313|EMBL:SFS11388.1};
GN   ORFNames=SAMN05192580_3573 {ECO:0000313|EMBL:SFS11388.1};
OS   Sphingomonas jatrophae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1166337 {ECO:0000313|EMBL:SFS11388.1, ECO:0000313|Proteomes:UP000198824};
RN   [1] {ECO:0000313|EMBL:SFS11388.1, ECO:0000313|Proteomes:UP000198824}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S5-249 {ECO:0000313|EMBL:SFS11388.1,
RC   ECO:0000313|Proteomes:UP000198824};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOZG01000003; SFS11388.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6M702; -.
DR   STRING; 1166337.SAMN05192580_3573; -.
DR   Proteomes; UP000198824; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Cell cycle {ECO:0000313|EMBL:SFS11388.1};
KW   Cell division {ECO:0000313|EMBL:SFS11388.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198824};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        31..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          72..183
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          239..516
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   573 AA;  61865 MW;  A7842370B3B52125 CRC64;
     MIHAALNPQT ARPVPARLAA DRADALTLAH FRLMVMMLIF IGVTAIVGLR LAYLSIFTDR
     PQASSGGAGL IPQRGDIVDR NGVVLARTID AWSIAVHPRK VIGDKRVIAA QLAELMPEKT
     GEQYFAILSA DKTYAYLRRR AVPELVRAVN AIGEPAIVFA REPERLYPQA TLASHVLGWI
     DQNGNAAAGM EKVLDSRLTA PALRDKPAAL SIDSRVQAAM ETELTAAMVK HQAIGASGLV
     LDVDTGEVVA MASLPSFNPN ATGRTPYETF LNKGVTNVYE LGSTFKMLTV ANALESGTVT
     SMARRYDATV PLQVGRFRIR DDHPEKRWLN VPEILVHSSN IGTARLADEL GPQRTRAFFH
     KLGFDRKVDI ELPAAGKPLW PGFWARTTTM TVAYGHGIAV TPLHLALAYA ALTNGGTLRP
     ATLIKQDKPV PGTRVISEAT SARMRQLMRL VVMKGTGKRA DAPGLRVGGK TGTAEKPQAG
     GYNRRVNVST FAAVFPMDHP RYVVIAMLDS PKGTADTFGF TTAAWVSGPV ISRVVARIGP
     LLGVIPDERR DVDESELLPL LWEPKGAKGH AAE
//