ID A0A1I6M8T3_9SPHN Unreviewed; 252 AA.
AC A0A1I6M8T3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=23S rRNA (Cytidine1920-2'-O)/16S rRNA (Cytidine1409-2'-O)-methyltransferase {ECO:0000313|EMBL:SFS12089.1};
GN ORFNames=SAMN05192580_3679 {ECO:0000313|EMBL:SFS12089.1};
OS Sphingomonas jatrophae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1166337 {ECO:0000313|EMBL:SFS12089.1, ECO:0000313|Proteomes:UP000198824};
RN [1] {ECO:0000313|EMBL:SFS12089.1, ECO:0000313|Proteomes:UP000198824}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S5-249 {ECO:0000313|EMBL:SFS12089.1,
RC ECO:0000313|Proteomes:UP000198824};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOZG01000003; SFS12089.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6M8T3; -.
DR STRING; 1166337.SAMN05192580_3679; -.
DR OrthoDB; 9784736at2; -.
DR Proteomes; UP000198824; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004538; Hemolysin_A/TlyA.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR NCBIfam; TIGR00478; tly; 1.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR Pfam; PF01479; S4; 1.
DR PIRSF; PIRSF005578; TlyA; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:SFS12089.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198824};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Transferase {ECO:0000313|EMBL:SFS12089.1}.
FT DOMAIN 5..67
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
SQ SEQUENCE 252 AA; 26776 MW; F6529F8D1FF4112A CRC64;
MPTTIRADQL LVERGLAESR ARAQALILAG HVFSGETKLA KAGQPVKPDA PLEVRGRDHP
WVSRGGIKLD HALTHFGWDV AGAVAMDVGS STGGFTDVLL SRGAAKVYAV DSGTNQLAWK
LRQDPRVVVL EQTNARHLTE AEIPEPIDLI VCDASFIALA KVLDTPLRFA APGARLVALV
KPQFEAGRGE VGKGGVVRDP AIHARVCDAA AEWVTAQGWQ VEGIVPSPIT GPEGNVEFLL
AARRAISDPL QD
//
