ID A0A1I6RD01_9BACL Unreviewed; 423 AA.
AC A0A1I6RD01;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:SFS62554.1};
GN ORFNames=SAMN05444972_1055 {ECO:0000313|EMBL:SFS62554.1};
OS Marininema halotolerans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC Marininema.
OX NCBI_TaxID=1155944 {ECO:0000313|EMBL:SFS62554.1, ECO:0000313|Proteomes:UP000198660};
RN [1] {ECO:0000313|EMBL:SFS62554.1, ECO:0000313|Proteomes:UP000198660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45789 {ECO:0000313|EMBL:SFS62554.1,
RC ECO:0000313|Proteomes:UP000198660};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR EMBL; FPAA01000005; SFS62554.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6RD01; -.
DR Proteomes; UP000198660; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF2; XANTHINE_URACIL PERMEASE-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 423 AA; 44017 MW; A9A35D539DEAD0C3 CRC64;
MQWLNPQAEG SSWKKEITAG LTSFFTAAYI VVVNPLILQD AGIPLGAGVV ATVAVSVFGC
LLMAFWARAP IIMIPAMGIN AFFTFTIVHS LGLSWQAGLG TVVISGILFL IAAMTPIGAK
LSEAVPSSLK HGITAGIGLF LAFIGLQKGA LIVPSTKSFV ALGDFTSPVA IITLAGLLFT
LVLYVRNVKG SFLLGILFIT LLSILTGTQS SGGLKETNFA DYSQVFFAAE FPLASLSFWI
AVFSLTMIVV FENMGLLTGM LPNKDRFSSS YKVTAVTSLA AGLFGTSPTI ASAESASGIA
EGGKTGIPAL VAGILFVGAA FSLPVLGMIP NNAAAPVLLI VGALMMQSVS HISFSDFSEG
FPAFLIIAGI PLTSSIADGL AFGFIAYPLL KVALGRWKQV PSLVYVIASM FLINLIATAL
TSH
//
