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Database: UniProt
Entry: A0A1I6T3B2_9CAUL
LinkDB: A0A1I6T3B2_9CAUL
Original site: A0A1I6T3B2_9CAUL 
ID   A0A1I6T3B2_9CAUL        Unreviewed;       301 AA.
AC   A0A1I6T3B2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Ubiquinone biosynthesis protein UbiV {ECO:0000256|HAMAP-Rule:MF_02233};
GN   Name=ubiV {ECO:0000256|HAMAP-Rule:MF_02233};
GN   ORFNames=SAMN05192570_2947 {ECO:0000313|EMBL:SFS83764.1};
OS   Brevundimonas viscosa.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Brevundimonas.
OX   NCBI_TaxID=871741 {ECO:0000313|EMBL:SFS83764.1, ECO:0000313|Proteomes:UP000198788};
RN   [1] {ECO:0000313|Proteomes:UP000198788}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.10683 {ECO:0000313|Proteomes:UP000198788};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for O(2)-independent ubiquinone (coenzyme Q)
CC       biosynthesis. Together with UbiU, is essential for the C6-hydroxylation
CC       reaction in the oxygen-independent ubiquinone biosynthesis pathway.
CC       {ECO:0000256|HAMAP-Rule:MF_02233}.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_02233};
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_02233}.
CC   -!- SUBUNIT: Forms an heterodimer with UbiU. {ECO:0000256|HAMAP-
CC       Rule:MF_02233}.
CC   -!- SIMILARITY: Belongs to the peptidase U32 family. UbiV subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_02233}.
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DR   EMBL; FOZV01000007; SFS83764.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6T3B2; -.
DR   STRING; 871741.SAMN05192570_2947; -.
DR   OrthoDB; 8523349at2; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000198788; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02233; UbiV; 1.
DR   InterPro; IPR001539; Peptidase_U32.
DR   InterPro; IPR043693; UbiV.
DR   PANTHER; PTHR30217; PEPTIDASE U32 FAMILY; 1.
DR   PANTHER; PTHR30217:SF11; UBIQUINONE BIOSYNTHESIS PROTEIN UBIV; 1.
DR   Pfam; PF01136; Peptidase_U32; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|HAMAP-Rule:MF_02233};
KW   Hydrolase {ECO:0000313|EMBL:SFS83764.1};
KW   Iron {ECO:0000256|HAMAP-Rule:MF_02233};
KW   Iron-sulfur {ECO:0000256|HAMAP-Rule:MF_02233};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_02233};
KW   Protease {ECO:0000313|EMBL:SFS83764.1};
KW   Ubiquinone biosynthesis {ECO:0000256|HAMAP-Rule:MF_02233}.
FT   BINDING         45
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_02233"
FT   BINDING         176
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_02233"
FT   BINDING         189
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_02233"
FT   BINDING         193
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_02233"
SQ   SEQUENCE   301 AA;  31422 MW;  4736E25F46D4169F CRC64;
     MTRPAIGLTL GPLLFHWSPP RIVDFYARIA DEAPVDRVYL GEVVCGKRAP LAAHALAEAA
     ERLTSAGKEV VWSGLALPAS VRDRRGIAAL AETPELVEVN DISGLLDRSA PFVAGPLLNV
     YNEAAAQELV ERGCVRLCAN VELSLEAVGA IARACPGLEI ELFAFGRVPL ALSGRCYHAR
     HHGLHKDSCQ FVCGWDADGL RLSTLEGRGF LAVNGVQTLS DGVQLADVDP AALADAGVAA
     LRLSPHTTDM AAVASAFRAF LDGGVDAGGL RGRVDALGLP GPIINGYLHG AAGMASVEAR
     P
//
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