ID   A0A1I6T9J7_9BACI        Unreviewed;       407 AA.
AC   A0A1I6T9J7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE            EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE   AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN   ORFNames=SAMN04488145_10499 {ECO:0000313|EMBL:SFS85881.1};
OS   Bacillus sp. 103mf.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1761751 {ECO:0000313|EMBL:SFS85881.1, ECO:0000313|Proteomes:UP000198993};
RN   [1] {ECO:0000313|EMBL:SFS85881.1, ECO:0000313|Proteomes:UP000198993}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=103MF {ECO:0000313|EMBL:SFS85881.1,
RC   ECO:0000313|Proteomes:UP000198993};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC         ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000799};
CC   -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC       {ECO:0000256|ARBA:ARBA00005297}.
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DR   EMBL; FPAF01000004; SFS85881.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6T9J7; -.
DR   STRING; 1761751.SAMN04488145_10499; -.
DR   Proteomes; UP000198993; Unassembled WGS sequence.
DR   GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR015890; Chorismate_C.
DR   InterPro; IPR004561; IsoChor_synthase.
DR   NCBIfam; TIGR00543; isochor_syn; 1.
DR   PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   SUPFAM; SSF56322; ADC synthase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235}.
FT   DOMAIN          123..390
FT                   /note="Chorismate-utilising enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00425"
FT   REGION          180..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          215..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   407 AA;  45100 MW;  B1EF17E88F004DAA CRC64;
     MMNHTTALRE LATKLLDDYK AGSSFFFASP YRTILAEGVF ATVEHNQVES FSELVHAVLN
     NAKQASHHNP IVVGALPFDR QRPVQLVVPQ ESRIADCLQF DAQDQVQLSS TLTYEMKPVP
     SPSEYMRGVE QGVEKIKAGD LKKIVLSRSL DLNSPEKVNI QKILRDLAKH NKHGYTFAVD
     LPKSEEEKNS DTAPQRSRTL IGASPELLVS RNGMQVVSNP LAGSRPRSED PAEDKRRAEE
     LLSSAKDLHE HAVVVEAVAV ALRPYCRILH VPEKPSLINS ETMWHLSTEV KGELFDTSVS
     SLELALALHP TPAVCGTPTE KAREAIKEIE PFDRRFFTGM LGWSDLNGDG EWIVTIRCAE
     IEENSLRLFA GAGIVAESKP VEELAETSAK FRTMLRAMGL NNELLEG
//