ID   A0A1I6TJU6_9SPHI        Unreviewed;      1957 AA.
AC   A0A1I6TJU6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=MG2 domain-containing protein {ECO:0000313|EMBL:SFS89532.1};
GN   ORFNames=SAMN05660206_106195 {ECO:0000313|EMBL:SFS89532.1};
OS   Sphingobacterium wenxiniae.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Sphingobacterium.
OX   NCBI_TaxID=683125 {ECO:0000313|EMBL:SFS89532.1, ECO:0000313|Proteomes:UP000198785};
RN   [1] {ECO:0000313|EMBL:SFS89532.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22789 {ECO:0000313|EMBL:SFS89532.1};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the protease inhibitor I39 (alpha-2-
CC       macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
CC       {ECO:0000256|ARBA:ARBA00010556}.
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DR   EMBL; FOZZ01000006; SFS89532.1; -; Genomic_DNA.
DR   STRING; 683125.SAMN05660206_106195; -.
DR   OrthoDB; 9767116at2; -.
DR   Proteomes; UP000198785; Unassembled WGS sequence.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 1.50.10.20; -; 1.
DR   Gene3D; 2.60.40.1930; -; 1.
DR   Gene3D; 2.170.130.10; TonB-dependent receptor, plug domain; 1.
DR   InterPro; IPR041246; Bact_MG10.
DR   InterPro; IPR001599; Macroglobln_a2.
DR   InterPro; IPR002890; MG2.
DR   InterPro; IPR037066; Plug_dom_sf.
DR   InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR   PANTHER; PTHR40094; ALPHA-2-MACROGLOBULIN HOMOLOG; 1.
DR   PANTHER; PTHR40094:SF1; UBIQUITIN DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00207; A2M; 1.
DR   Pfam; PF17973; bMG10; 1.
DR   Pfam; PF01835; MG2; 1.
DR   SMART; SM01360; A2M; 1.
DR   SUPFAM; SSF56935; Porins; 1.
DR   SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198785}.
FT   DOMAIN          1231..1321
FT                   /note="Alpha-2-macroglobulin"
FT                   /evidence="ECO:0000259|SMART:SM01360"
SQ   SEQUENCE   1957 AA;  225135 MW;  2844E73E5AE465AE CRC64;
     MKSLFISVII SILPLLGLAQ SFEAQWKEVE RLIQIKNYAQ TQPILSAIKR DAKATGNSPE
     WIRAILAEHH ALTVNMTTDS AFYRVQRHFE EQLSIANKIE KNILNNLYAQ FLSRNIFQTR
     VENTGHFLSW EENRRKSFVD SIFNSSLNDP DLLLKQPIEK WHTLLSHQQN QSLAPTVYHL
     LVYAYNDFLN SYGSAKEINK NGTLLFNSLQ QINKTQGYTN AYAYLLFYPY THTNLWEIHR
     QETQIEKLLN DHQSDYNAHI LLLLANAWKI HDDNRKAIQY LNKALQDYPT SPWADDVKKL
     YDELTQASAT MEISNFALPN KYTPVKLHAR NTDKVFIRVY NITNTPQSYK EYKTQYDSLS
     HRVNINAPLS YEETVYLKSF DDYNSHITNY KINPLPYGNY KVLIANNPDF LDNGQEYDVS
     QIDFIVSNIF VSPVIEAEGN HTTDYLYTTL LVNRKTGLPY ANENISLYYF EKDKPTQIST
     LKTDKNGVFN YLADYHKNRY ELEDQLLFIP SEDQFIPLDY LNNIPNHIRE QETKTPQNDA
     LLLIDRAIYR PGQEVFFKAI LYIDDALKGK VIPNQSVKIV HKDANDQPID TLNLVTNAFG
     SVDGRFQIPQ KTLNGSFHLE IHQNNRLLAE KYYSVEEYKR PTFKVSFNEN KNTYTKQDTA
     RFTGTVETLS GASLSHTSVK YKVSFYDEEH YKQIDYVDSI TTTDLNGKFT FNIPLTDPIF
     HSQKEISLQF YAEAINETGE IQQGYGSYNY ADQPLDIAII TPSPIAAEKW ENIIVKTTNP
     NGFPLSAKGI LHVYKYDSPT IIQSDRKAFD FKSEYHILDT ADYQTYFPHD FDKQDIMTER
     PKTLVGTFAF ESTGIDTVRI DSKHYTYGSY LIEAHSIQGS DTIKASRTIQ LFIENSQKTT
     DKEFLTVQLD RSTYAIGDKV TMDFKTDFEQ AGGIYLWKVK GDTKSPVVFL PFKGGHTSYT
     QSISEEDFQH NTWFEIMMMQ ENKMVTRRKN IPIIRTDKSL AIQTNTFRDK ITPGQKETWS
     FTIKNKENKT DNIEVLASMY DTALDQFREH TFPSVFPLSR NSYWHQIRSG WSMYNYNHYI
     PAHNLFSNNW DRQISMRPPS PPTFRNYGLG ETNLMFIGGE GTLDEVVVVG YDGDFTDRLE
     SNTSGVAVRG AVSTNSEQQP LYIIDGNIIV DFKQNTLSSD DIHTISVLQS EEAVAIYGAD
     AANGAILIIT KEGHKVNQLA QAQTRSNLQE TAFFLPDLHT DAEGNIRFTF ESPEALTRWK
     LMLFAHTEDL KAGTSSFFTQ TQKQLMVRPN LPRFLREGDE IVIKSQIQNL STVIQTGTAK
     LEIINPENNE VISAAFFNDT ELRDFSVEAK GNTMVSWKLQ IPKDYPIVQI KVVGATEEFS
     DGEVHELAIL PNRILITDSR KIVLESDQSD TFTIPAAAKD NLQAKIQIQS NPILEIISAL
     DYLKNYPYEC NEQIASKWYA LKMLQYIQSH YPSIHNYFDR INPDKATTKL EENSTLSELV
     IAEMPWVKQI QNDKDKVKSL ARLFKTNFRS EIYTLEQKLQ KAQLENGAFS WFSGGKSDTN
     ISIRLLEIFG KVGKLDEALI TDDIRNIGRQ LIHFLDQDTT VYGTHASTQI ALDYLYARSL
     WNEQPLSTEK IEHLRKHIDL TSSYTADQPA GFAAKAWLVN MQYDYCIASV EVKNRILQEA
     IYDQERGMYW ESNARYYNSM SMQSYMIEAY KQLDSTKLDY IAQWVYYSKQ NEHWKTTWNT
     VDAIYALLLT NNPLDFTLDN NVSIAIDNKP VITDDKVLGQ VSKVLTSAEL RTDKAINIIN
     NNNRKIYGGI YHQYFVSLKD VRSTQKELSI SKKVFVQKGA EWIESTSFKT GDKIKVQLMV
     VNNEPLHYVH LRDDRAAGFE PVYQSSGYQF WKGYYFTIND ASTNYFFDFL PPGRHLYEYE
     VKTNNSGSFS SGIAQIIGMY NPTVNARSGN ISIKIEE
//