ID   A0A1I6TNA3_9RHOB        Unreviewed;       447 AA.
AC   A0A1I6TNA3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Zinc protease {ECO:0000313|EMBL:SFS90655.1};
GN   ORFNames=SAMN04488040_2362 {ECO:0000313|EMBL:SFS90655.1};
OS   Sulfitobacter marinus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Sulfitobacter.
OX   NCBI_TaxID=394264 {ECO:0000313|EMBL:SFS90655.1, ECO:0000313|Proteomes:UP000199239};
RN   [1] {ECO:0000313|Proteomes:UP000199239}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23422 {ECO:0000313|Proteomes:UP000199239};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
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DR   EMBL; FPAJ01000003; SFS90655.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6TNA3; -.
DR   STRING; 394264.SAMN04488040_2362; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000199239; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:SFS90655.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199239};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..447
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011590423"
FT   DOMAIN          39..184
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          193..376
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   447 AA;  50017 MW;  7C1E33E91BC5A6D4 CRC64;
     MIRFPALAAF VSFLLPSSAG LAAQNEAVTH FTLDNGMEVV VIEDHRSPSV QQMVWYRAGS
     ADEPKGSSGV AHFLEHLLFK ATDKMESGEF SATVAKNGGR DNAFTSYDYT AYFQRVAADR
     LELMMQMESD RMRNIRLTHD DIETERDVII EERNQRTENS PGALFQEQMS AAQYLNHQYG
     APVIGWMHEM QTLDLEDALG FYELYYSPNN AILVVSGDVE PAKVHRLAKQ YYGVIPANPD
     LPERLRTQEP PQTAERRVIF RDSRVAQEYI SRSYLAQERD PGNQKTAAAL TILAEILGGG
     TTSYLAEKLQ FDTQIATYSS AYYRGQALDD TTFNLVVVPR LDVTLEAAED AMDAAVSTFL
     EEGVDPEQLE RIKAQLRADQ VYSRDSAEKV ANRYGSALAI GLSVQDVQDW PDILEAVTAE
     DIMQAARDVF DCEASVTGWL MREEVTQ
//