ID   A0A1I6TYR4_9BACI        Unreviewed;       647 AA.
AC   A0A1I6TYR4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE            EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN   ORFNames=SAMN04488145_105192 {ECO:0000313|EMBL:SFS94332.1};
OS   Bacillus sp. 103mf.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1761751 {ECO:0000313|EMBL:SFS94332.1, ECO:0000313|Proteomes:UP000198993};
RN   [1] {ECO:0000313|EMBL:SFS94332.1, ECO:0000313|Proteomes:UP000198993}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=103MF {ECO:0000313|EMBL:SFS94332.1,
RC   ECO:0000313|Proteomes:UP000198993};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FPAF01000005; SFS94332.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6TYR4; -.
DR   STRING; 1761751.SAMN04488145_105192; -.
DR   OrthoDB; 9778383at2; -.
DR   Proteomes; UP000198993; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   CDD; cd05968; AACS_like; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR   PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          30..86
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          97..472
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          530..608
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   647 AA;  72593 MW;  F7E595CFD5AF7D77 CRC64;
     MKQAVWFPAE EYKANTRLYQ WMQSLGYDDY ETFYEKSIED PAWFWEAAER AVGYQWMRPY
     TEVLDLANGM PFAKWYVDGT CNVVESALSR WIAEDDTKTK QALIWEGENG TSKSFTYEEL
     DNWVSRVANG LKHLGIEKGD RVTIYMPMIP ETVVAMLAVM KIGAIISPIF SGFASDAVMT
     RVQAAGSKMI ITADGFARRG KTVSLKEEVD KACEHCPSVE KVVIVRHAGN EFTPQDYDIS
     WSVLEKDKPF THAEEMKSDD PLMLIYTSGT TGKPKGTVHT HAGFPLKAAF DAGFGMNVKQ
     GDRVLWITDM GWMMGPFLLF GSLLNGATMV IYEGVPDYPE TDRLWEMVDR YEVTHLGISP
     TLIRSLMAKG DSWVKKHSLH SLEVIGSTGE PWNPDPWMWL FETVCKGRVP ICNYSGGTEI
     SGGIFGNVLI KPIAPISFNA SLPGMAAVVL DENGVPVQNE VGELCLEKPW VGMTKSFWEE
     DDRYVNTYWS RFENKWVHGD WVLYDGEQYI ITGRSDDTLN IAGKRIGPAE YESILVKHHD
     VIEAGAIGVP DEVKGEVCHC FVVLREGTVF TPELKKELLS LVNSHIGKAL CPKDIHAVED
     LPKTRNSKVM RRVIKAAYLG KELGDLSSLV NPEVVAYIQG IQSQKQR
//