ID A0A1I6U9I7_9PSEU Unreviewed; 828 AA.
AC A0A1I6U9I7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpC {ECO:0000313|EMBL:SFS97937.1};
GN ORFNames=SAMN05660874_04728 {ECO:0000313|EMBL:SFS97937.1};
OS Saccharopolyspora flava.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=95161 {ECO:0000313|EMBL:SFS97937.1, ECO:0000313|Proteomes:UP000198852};
RN [1] {ECO:0000313|EMBL:SFS97937.1, ECO:0000313|Proteomes:UP000198852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44771 {ECO:0000313|EMBL:SFS97937.1,
RC ECO:0000313|Proteomes:UP000198852};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homohexamer. The oligomerization is ATP-dependent.
CC {ECO:0000256|ARBA:ARBA00026057}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
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DR EMBL; FOZX01000009; SFS97937.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6U9I7; -.
DR STRING; 95161.SAMN05660874_04728; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000198852; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Hydrolase {ECO:0000313|EMBL:SFS97937.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:SFS97937.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 35..176
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 444..479
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 153..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 828 AA; 89522 MW; 2C3E8EC447336538 CRC64;
MATFFGPVGG PFDEYFARFF GADDSTAGSR RVDITELMTE QAQQLVGEAA KFARDRGQGS
LDALHLLWSA AKQDPTRAQL SQLGVDTEAF AKEVEGHLPA SGTPVEDESV SLTLAARTAL
ADAHRVARAL GSTYIGPQHL LLALSANPET EAGRLLGGAG AGPEALRDAT QRPAPQQAPK
SGPSGGETPT LDEYGRDLTA TAREGGLDPV IGRADEIEQT IEILSRRTKN NPVLVGEAGV
GKTAIVEGLA QRIASGDVPE VLTGKRVVQL DLSAMLSGTR YRGDFEERMT KVIDEISEHS
GELIVFIDEL HTVVGAGGAE GAMDAGNMLK PRLARGELHI VGATTLDEYR KNIEKDPALE
RRFQPVQVPE PSVADTITIL RGLQEQYEKH HKVSYTEEAV EAAAKLSDQY INDRFLPDKA
IDLIDQAGAR KRLNSGVADD GELRAKVERL EQLKNEAVAS EDYERASALR DEITAAQERL
NEGGSGVLEI GPADIAEVVS RATGVPVSRL TAEEKVRLRN LESELHQRVV GQDDAVRALA
RAVRRSRSGL GDPSRPVGSF LFLGPTGVGK TELAKALAES LFGDEQRMIR LDMSEFQERH
TASRLVGAPP GYVGHGEAGE LTEAVRRSPY SVVLLDEIEK AHPDVFNTLL QVLDDGRLTD
GQGRTVDFSN TVLIMTSNLA SEVVSSAGGK IGFTAGSPTQ DLEERVMPKL KDAFRPEFLN
RINEIVVFKR LDGEQLHTIT RALLETTTKR LADMGVEVVF DDDAVAWVAD RGYQPEFGAR
PLRRAIEREV DDRISDLLLD GELTEGTRLR VGARDGALDF QVEAPVAA
//
