ID   A0A1I6UW29_9PSEU        Unreviewed;       566 AA.
AC   A0A1I6UW29;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Glycine/sarcosine N-methyltransferase {ECO:0000313|EMBL:SFT05641.1};
GN   ORFNames=SAMN05660874_05345 {ECO:0000313|EMBL:SFT05641.1};
OS   Saccharopolyspora flava.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=95161 {ECO:0000313|EMBL:SFT05641.1, ECO:0000313|Proteomes:UP000198852};
RN   [1] {ECO:0000313|EMBL:SFT05641.1, ECO:0000313|Proteomes:UP000198852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44771 {ECO:0000313|EMBL:SFT05641.1,
RC   ECO:0000313|Proteomes:UP000198852};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOZX01000013; SFT05641.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6UW29; -.
DR   STRING; 95161.SAMN05660874_05345; -.
DR   OrthoDB; 279734at2; -.
DR   Proteomes; UP000198852; Unassembled WGS sequence.
DR   GO; GO:0017174; F:glycine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   CDD; cd02440; AdoMet_MTases; 2.
DR   Gene3D; 3.30.46.10; Glycine N-methyltransferase, chain A, domain 1; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR014369; Gly/Sar_N_MeTrfase.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR16458; GLYCINE N-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR16458:SF2; GLYCINE N-METHYLTRANSFERASE; 1.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR   PROSITE; PS51600; SAM_GNMT; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:SFT05641.1};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SFT05641.1}.
FT   DOMAIN          83..181
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13649"
FT   DOMAIN          360..458
FT                   /note="Methyltransferase type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08241"
SQ   SEQUENCE   566 AA;  64467 MW;  02C208B71798A500 CRC64;
     MAKSVEDAAS NEVGTPDMAE LVAREEQVFG ENPLEVRESD HYTHEYVGGF VEKWDDLIDW
     KKRYESEGSF FIDQLKARGV KSVLDAATGT GFHSVRLLEE GFETVSADGS PQMLAKAFQN
     GLEYGGHILR VVNADWRWLN RDVHGEYDAI ICLGNSFTHL FSERDRRKTL AEFYAMLKHD
     GVLIIDQRNY DSILDDGFSS KHTYYYAGED VSAEPDYVDE GLARFKYTFP DKSEFFLNMY
     PLRKNYTRRL LREVGFQRID TYGDFQETYQ DGEPDFFIHV AEKKYRPDEE LSDVYSTAVH
     TARDYYNSED ADNFYYHVWG GNDIHVGLYS SDTEDIDTAS RRTVERMCSK VEITPETRIL
     DIGAGYGGAA RHLARAYGCK VSCLNLSEVE NARNVEFNRA EGLEDLIEVK DGSFEDIPFQ
     DNAFDIVWSQ DAILHSGDRP RVLEEVARVL KPTGSFLFTD PMASDTAKRS DLGPILDRLS
     LDTMGSPGFY RRELARLGLQ NFEFDDLTEY LAIHYGRVLQ ELEAREGDLA DKISDAYRTK
     MKTGLKNWVS GGKAGNLAWG IIHARV
//