ID A0A1I6VUT1_9ACTN Unreviewed; 244 AA.
AC A0A1I6VUT1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:QKV71092.1};
DE SubName: Full=Transcriptional regulator, IclR family {ECO:0000313|EMBL:SFT17164.1};
GN ORFNames=HUT13_21760 {ECO:0000313|EMBL:QKV71092.1}, SAMN05444716_11013
GN {ECO:0000313|EMBL:SFT17164.1};
OS Streptomyces harbinensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1176198 {ECO:0000313|EMBL:SFT17164.1, ECO:0000313|Proteomes:UP000198873};
RN [1] {ECO:0000313|EMBL:SFT17164.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7047 {ECO:0000313|EMBL:SFT17164.1};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000198873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7047 {ECO:0000313|Proteomes:UP000198873};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QKV71092.1, ECO:0000313|Proteomes:UP000509706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA02264 {ECO:0000313|EMBL:QKV71092.1,
RC ECO:0000313|Proteomes:UP000509706};
RA Zhang B., Shi J., Ge H.;
RT "Genome mining for natural products.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP054938; QKV71092.1; -; Genomic_DNA.
DR EMBL; FPAB01000010; SFT17164.1; -; Genomic_DNA.
DR RefSeq; WP_026047726.1; NZ_FPAB01000010.1.
DR AlphaFoldDB; A0A1I6VUT1; -.
DR STRING; 1176198.SAMN05444716_11013; -.
DR KEGG; shar:HUT13_21760; -.
DR Proteomes; UP000198873; Unassembled WGS sequence.
DR Proteomes; UP000509706; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF39; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198873};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..70
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 71..240
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 244 AA; 25468 MW; 170AA2BAC636DFB1 CRC64;
MDNSRGDSSG VGVLDKAALV LGALESGPAT LAGLVSATGL ARPTAHRMAV ALEHHRLLAR
DMQGRFVLGP RLAELAAAAG EDRLLAAAGP VLTHLRDLTG ESAQLYRRQG DMRICVAAAE
RLSGLRDTVP VGSTLPMKAG SAAQILLAWE EPERLHHGLQ GARFTATALS GVRRRGWAQS
IGEREPGVAS VSAPVRGPSN RVVAAVSVSG PIERLTRHPG RMHAQALIDA AGRLTEALRR
GGGH
//
