ID   A0A1I6WHK0_9BACL        Unreviewed;       986 AA.
AC   A0A1I6WHK0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Serine protease, subtilisin family {ECO:0000313|EMBL:SFT25458.1};
GN   ORFNames=SAMN05428962_5842 {ECO:0000313|EMBL:SFT25458.1};
OS   Paenibacillus sp. BC26.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1881032 {ECO:0000313|EMBL:SFT25458.1, ECO:0000313|Proteomes:UP000199637};
RN   [1] {ECO:0000313|EMBL:SFT25458.1, ECO:0000313|Proteomes:UP000199637}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BC26 {ECO:0000313|EMBL:SFT25458.1,
RC   ECO:0000313|Proteomes:UP000199637};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC       ProRule:PRU01240, ECO:0000256|RuleBase:RU003355}.
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DR   EMBL; FPAD01000005; SFT25458.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I6WHK0; -.
DR   STRING; 1881032.SAMN05428962_5842; -.
DR   Proteomes; UP000199637; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.380; -; 3.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR   InterPro; IPR022398; Peptidase_S8_His-AS.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR001119; SLH_dom.
DR   PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR   PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   Pfam; PF00395; SLH; 3.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF89260; Collagen-binding domain; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51272; SLH; 3.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00136; SUBTILASE_ASP; 1.
DR   PROSITE; PS00137; SUBTILASE_HIS; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}.
FT   DOMAIN          811..869
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|PROSITE:PS51272"
FT   DOMAIN          870..933
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|PROSITE:PS51272"
FT   DOMAIN          934..986
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|PROSITE:PS51272"
FT   REGION          62..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        201
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        234
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        392
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ   SEQUENCE   986 AA;  105112 MW;  3571586C61B85FAE CRC64;
     MPTLVCKDTF YSAMRHSGRL RFAAAAAFAP RRALLHAALA ALLLWSAPAG AAPAAAAGAA
     PAASPPAAAT AGPPGAAQPA AGGGQDEPAP PGGWLIKWRD PALAKPLPGT RLLRRLAMPA
     AGAVDVVRPE DPGADTSEWL LRLQRMPEIA YAEPIGSVKL LAAPASNDPE LPKLQHLDQI
     GALTAWSKVH DQLDLTIALI DTGVDLDHPD LKNNLVAGTN LVSPGKPPED DNGHGTAVAG
     VLAGEGNNKE GIAGILWRAK LMPIKALDAD GFGDEERLGK AIVYAVDHGA RIIVLSVGLY
     RYSPYLRDIV QYAESKGALL VAASGNDGLA LGSKAEVKYP AAYATVLAVA GVDADGKPES
     RSNAGPEIDI AAPWHVYTTA LGGGYKHEEG TSMAAPQAAA AAALVWAVHP GYKPYQVRAL
     LRQTAKDIGK QGVDDASGYG LLQIDRAVTG VLRADGYEPN DTRQTAHKFP LGKRIAAELA
     GGQDKDWYTL DAPYDGVISL QIQGLLSGGE TTPILQMTHV VGGVVQGTKV TKLGNQTVEW
     NVKKGRNEFE LHYFDSTAKQ RLPYLLTSSF EIAPDSYEVN DKQYQAFTLK PQSQQVTGNF
     HQTGDRDWYA IHFETGGTLK LSLSTDSARI DPALAFGRQG ATLQEIDENS EGETESSEPI
     NVTPGIYYIR VHNGMSAQAG PSAASYTLHI ELISKYTDPN EPNNKAYEAT GVAKGSDYWG
     VMGAEDADWY QLRLGSESVL SVQVTGIPSG IRMKAEVFDK RQKPLFTLQS AKNETGMVKE
     QRVQAGLYYV KVTASGSFDR QYYGFRMDAE QVVAGFRDIT GHWAADTIVA LSKDGIVEGS
     GNYRFYPNRS ITRAEAISML VRALNPSASA GPGFTDVTSK HWAYAAITKA SGTGWVGGYP
     GGAFGPGKPI TREEMAVILL RALQLNSARP YAATFKDVKL TRWSAPAIQT MKQKALLGGY
     PDGSFRPEQT ASRAEFAALL LRAMNM
//